Effect of Motor Activity Restriction on Copper Content in Rats.

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2025-01-01 Epub Date: 2025-02-13 DOI:10.1007/s10517-025-06326-w

R I Zaripova, G G Yafarova, V V Andrianov, M I Sungatullina, N I Ziyatdinova, Kh L Gainutdinov, T L Zefirov

引用次数: 0

Abstract

In rats subjected to increasing restriction of motor activity starting from day 21 days of life, copper content was evaluated by electron paramagnetic resonance (EPR) spectroscopy by analyzing the levels of copper-containing paramagnetic complexes in the heart and liver tissues. Copper content was assessed by the intensity of the characteristic EPR signal from the Cu²⁺-diethyldithiocarbamate complex (Cu²⁺-(DETC)₂). It was found that after restriction of motor activity for 30 days, copper content in the heart and liver tissues increased by 2.2 and 2.9 times, respectively.

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来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.