Marluce Rodrigues Godinho, Fábio da Costa Carbogim, Angélica da Conceição Oliveira Coelho, Gabriela Do Nascimento Martins de Araujo, Amanda Damasceno de Souza, Helen Vaz da Silva Gomes, Alice Maria Das Graças de Sousa, Herlander Jesus Borges Tomás Rodrigues, Kelli Borges Dos Santos, Rui Pedro Gomes Pereira
{"title":"Effect of aspiration during intramuscular injection on the occurrence of adverse effects in adults: a systematic review protocol.","authors":"Marluce Rodrigues Godinho, Fábio da Costa Carbogim, Angélica da Conceição Oliveira Coelho, Gabriela Do Nascimento Martins de Araujo, Amanda Damasceno de Souza, Helen Vaz da Silva Gomes, Alice Maria Das Graças de Sousa, Herlander Jesus Borges Tomás Rodrigues, Kelli Borges Dos Santos, Rui Pedro Gomes Pereira","doi":"10.11124/JBIES-23-00225","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review is to evaluate the effect of prior aspiration vs no aspiration during intramuscular injection on the occurrence of adverse effects in adult patients.</p><p><strong>Introduction: </strong>Aspiration is a procedure conducted prior to the administration of intramuscular medications that aims to ensure that the needle tip is inserted in the proper place. Although aspiration is a common procedure, questions have been raised about adverse effects.</p><p><strong>Inclusion criteria: </strong>This review will consider experimental and observational studies that include or evaluate the occurrence of any adverse effects following intramuscular injection, either with or without prior syringe aspiration, in adult patients. Adverse effects will include local pain, induration, puncture of blood vessels, decreased drug effect, hematoma, or abscess. The review will exclude studies on venipuncture, aspiration biopsies, or other invasive punctures of a diagnostic nature.</p><p><strong>Methods: </strong>This review will be conducted in accordance with the JBI methodology for systematic reviews of effectiveness. Databases to be searched will include PubMed, Embase, CINAHL, Scopus, LILACS, and Web of Science Core Collection, as well as sources of unpublished/gray literature, with no date or language limitations. Two independent reviewers will conduct study selection, critical appraisal, and data extraction. Studies will, where possible, be pooled in statistical meta-analysis. The grading of the certainty of evidence will be determined using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.</p><p><strong>Registration number: </strong>PROSPERO CRD42021270432.</p>","PeriodicalId":36399,"journal":{"name":"JBI evidence synthesis","volume":"23 2","pages":"394-400"},"PeriodicalIF":1.5000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JBI evidence synthesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11124/JBIES-23-00225","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/12 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The objective of this review is to evaluate the effect of prior aspiration vs no aspiration during intramuscular injection on the occurrence of adverse effects in adult patients.
Introduction: Aspiration is a procedure conducted prior to the administration of intramuscular medications that aims to ensure that the needle tip is inserted in the proper place. Although aspiration is a common procedure, questions have been raised about adverse effects.
Inclusion criteria: This review will consider experimental and observational studies that include or evaluate the occurrence of any adverse effects following intramuscular injection, either with or without prior syringe aspiration, in adult patients. Adverse effects will include local pain, induration, puncture of blood vessels, decreased drug effect, hematoma, or abscess. The review will exclude studies on venipuncture, aspiration biopsies, or other invasive punctures of a diagnostic nature.
Methods: This review will be conducted in accordance with the JBI methodology for systematic reviews of effectiveness. Databases to be searched will include PubMed, Embase, CINAHL, Scopus, LILACS, and Web of Science Core Collection, as well as sources of unpublished/gray literature, with no date or language limitations. Two independent reviewers will conduct study selection, critical appraisal, and data extraction. Studies will, where possible, be pooled in statistical meta-analysis. The grading of the certainty of evidence will be determined using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
目的：本综述的目的是评估成人患者在肌内注射过程中既往抽吸与未抽吸对不良反应发生的影响。简介：抽吸是在肌肉注射药物之前进行的一项程序，目的是确保针尖插入适当的位置。虽然抽吸是一种常见的手术，但其副作用也引起了人们的质疑。纳入标准：本综述将考虑实验和观察性研究，包括或评估成年患者肌肉注射后任何不良反应的发生，无论是否事先有注射器抽吸。不良反应包括局部疼痛、硬化、血管穿刺、药物效果下降、血肿或脓肿。该审查将排除静脉穿刺、穿刺活检或其他具有诊断性质的侵入性穿刺的研究。方法：本综述将按照JBI方法进行系统的有效性评价。检索的数据库包括PubMed、Embase、CINAHL、Scopus、LILACS和Web of Science Core Collection，以及未发表/灰色文献的来源，没有日期或语言限制。两名独立审稿人将进行研究选择、批判性评估和数据提取。在可能的情况下，研究将汇总在统计荟萃分析中。证据确定性的分级将使用分级建议评估、发展和评价（GRADE）方法来确定。注册号：普洛斯彼罗CRD42021270432。
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