Unresolved ethical issues of genetic counseling and testing in clinical psychiatry.

IF 1.5 4区医学 Q4 GENETICS & HEREDITY

Psychiatric Genetics Pub Date : 2025-02-05 DOI:10.1097/YPG.0000000000000385

Julia Perry, Eline Bunnik, Marcella Rietschel, Heidi Beate Bentzen, Charlotta Ingvoldstad Malmgren, Joanna Pawlak, Boris Chaumette, Kristiina Tammimies, Filip Bialy, Virginia Bizzarri, Isabella Borg, Domenico Coviello, David Crepaz-Keay, Eliza Ivanova, Andrew McQuillin, Signe Mežinska, Maria Johansson Soller, Jaana Suvisaari, Melanie Watson, Katrine Wirgenes, Sarah L Wynn, Franziska Degenhardt, Silke Schicktanz

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引用次数: 0

Abstract

Objective: This position article discusses current major ethical and social issues related to genetic counseling and testing in clinical psychiatry (PsyGCT).

Methods: To address these complex issues in the context of clinical psychiatry relevant to PsyGCT, the interdisciplinary and pan-European expert Network EnGagE (Enhancing Psychiatric Genetic Counseling, Testing, and Training in Europe; CA17130) was established in 2018. We conducted an interdisciplinary, international workshop at which we identified gaps across European healthcare services and research in PsyGCT; the workshop output was summarized and systematized for this position article.

Results: Four main unresolved ethical topics were identified as most relevant for the implementation of PsyGCT: (1) the problematic dualism between somatic and psychiatric disorders, (2) the impact of genetic testing on stigma, (3) fulfilling professional responsibilities, and (4) ethical issues in public health services. We provide basic recommendations to inform psychiatrists and other healthcare professionals involved in the clinical implementation of PsyGCT and conclude by pointing to avenues of future ethics research in PsyGCT.

Conclusion: This article draws attention to a set of unresolved ethical issues relevant for mental health professionals, professionals within clinical genetics, patients and their family members, and society as a whole and stresses the need for more interdisciplinary exchange to define standards in psychiatric counseling as well as in public communication. The use of PsyGCT may, in the future, expand and include genetic testing for additional psychiatric diagnoses. We advocate the development of pan-European ethical standards addressing the four identified areas of ethical-practical relevance in PsyGCT.

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摘要这篇立场文章讨论了当前与临床精神病学（PsyGCT）中的遗传咨询和检测相关的主要伦理和社会问题：为了解决临床精神病学中与 PsyGCT 相关的这些复杂问题，2018 年成立了跨学科和泛欧洲专家网络 EnGagE（加强欧洲精神病学遗传咨询、检测和培训；CA17130）。我们举办了一次跨学科的国际研讨会，会上我们找出了欧洲医疗保健服务和 PsyGCT 研究中存在的差距；研讨会的成果经过总结和系统化，形成了这篇立场文章：结果：我们确定了与实施 PsyGCT 最为相关的四个尚未解决的主要伦理问题：(1) 躯体疾病和精神疾病之间的二元论问题，(2) 基因检测对耻辱感的影响，(3) 履行专业责任，以及 (4) 公共卫生服务中的伦理问题。我们提出了一些基本建议，供参与 PsyGCT 临床实施的精神科医生和其他医疗保健专业人员参考，并在最后指出了未来 PsyGCT 伦理学研究的途径：本文提请人们注意一系列尚未解决的伦理问题，这些问题与精神卫生专业人员、临床遗传学专业人员、患者及其家庭成员以及整个社会都息息相关，并强调需要进行更多的跨学科交流，以确定精神科咨询以及公共交流的标准。未来，PsyGCT 的使用范围可能会扩大，包括对其他精神病诊断的基因检测。我们主张制定泛欧伦理标准，以解决已确定的与 PsyGCT 伦理实践相关的四个领域的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychiatric Genetics 医学-神经科学

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： The journal aims to publish papers which bring together clinical observations, psychological and behavioural abnormalities and genetic data. All papers are fully refereed. Psychiatric Genetics is also a forum for reporting new approaches to genetic research in psychiatry and neurology utilizing novel techniques or methodologies. Psychiatric Genetics publishes original Research Reports dealing with inherited factors involved in psychiatric and neurological disorders. This encompasses gene localization and chromosome markers, changes in neuronal gene expression related to psychiatric disease, linkage genetics analyses, family, twin and adoption studies, and genetically based animal models of neuropsychiatric disease. The journal covers areas such as molecular neurobiology and molecular genetics relevant to mental illness. Reviews of the literature and Commentaries in areas of current interest will be considered for publication. Reviews and Commentaries in areas outside psychiatric genetics, but of interest and importance to Psychiatric Genetics, will also be considered. Psychiatric Genetics also publishes Book Reviews, Brief Reports and Conference Reports.