Exploring the homing effect and enhanced drug delivery potential of small extracellular vesicles.

Abstract

We propose a strategy of assembling small extracellular vesicles (sEVs) and liposomes into dimers to explore the homing effect and the drug delivery potential of sEVs. The uptake rate of dimers by parental cells is 2.6-4.9 times higher than that by other cells, showing enhanced drug delivery capacity.