Mpox: Global epidemic situation and countermeasures.

IF 5.5 1区农林科学 Q1 IMMUNOLOGY

Virulence Pub Date : 2025-12-01 Epub Date: 2025-02-08 DOI:10.1080/21505594.2025.2457958

Wenshuang Hou, Nan Wu, Yanzhi Liu, Yanjun Tang, Quan Quan, Yinghua Luo, Chenghao Jin

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引用次数: 0

Abstract

Mpox, is a zoonotic disease caused by the monkeypox virus and is primarily endemic to Africa. As countries gradually stop smallpox vaccination, resistance to the smallpox virus is declining, increasing the risk of infection with mpox and other viruses. On 14 August 2024, the World Health Organization announced that the spread of mpox constituted a public health emergency of international concern. Mpox's transmission routes and symptoms are complex and pose new challenges to global health. Several vaccines (such as ACAM2000, JYNNEOS, LC16m8, and genetically engineered vaccines) and antiviral drugs (such as tecovirimat, brincidofovir, cidofovir, and varicella immunoglobulin intravenous injection) have been developed and marketed to prevent and control this disease. This review aims to introduce the epidemic situation, epidemiological characteristics, physiological and pathological characteristics, and preventive measures for mpox in detail, to provide a scientific basis for the prevention and control of mpox viruses worldwide.

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来源期刊

Virulence IMMUNOLOGY-MICROBIOLOGY

CiteScore

9.20

自引率

1.90%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Virulence is a fully open access peer-reviewed journal. All articles will (if accepted) be available for anyone to read anywhere, at any time immediately on publication. Virulence is the first international peer-reviewed journal of its kind to focus exclusively on microbial pathogenicity, the infection process and host-pathogen interactions. To address the new infectious challenges, emerging infectious agents and antimicrobial resistance, there is a clear need for interdisciplinary research.