Impact of repeat testing in tuberculosis patients with a trace call on Xpert MTB/RIF Ultra: a retrospective cohort study.

IF 1.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-06-05 DOI:10.1093/trstmh/traf002

Suyash Jha, Nitin Gupta, Tirlangi Praveen Kumar, Kiran Chawla, Vishnu P Shenoy, Muralidhar Varma, Mohan K Manu

引用次数: 0

Abstract

Background: This study aimed to see if rifampicin susceptibility can be determined on repeat sampling in pulmonary tuberculosis with a trace call on the first GeneXpert Ultra report.

Methods: This retrospective cohort study included adults with a GeneXpert Ultra trace call in the first respiratory sample from January 2021 to June 2024.

Results: Of the 27 patients with repeat sampling done after the initial trace call, rifampicin susceptibility could be determined in 37% (n=10) of patients.

Conclusions: Repeating GeneXpert Ultra testing in patients with an initial trace call is valuable for determining rifampicin susceptibility.

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Xpert MTB/RIF Ultra对肺结核患者重复检测的影响：一项回顾性队列研究

背景：本研究旨在观察是否可以通过重复采样确定利福平对肺结核的敏感性，并根据GeneXpert Ultra报告的首次痕量呼叫。方法：这项回顾性队列研究纳入了2021年1月至2024年6月首次呼吸样本中使用GeneXpert Ultra追踪呼叫的成年人。结果：在27例患者中，首次微量呼叫后重复取样的患者中，37% （n=10）的患者可确定利福平敏感性。结论：对初始痕量呼叫的患者重复GeneXpert Ultra检测对于确定利福平的敏感性是有价值的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transactions of The Royal Society of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.00

自引率

9.10%

发文量

115

审稿时长

4-8 weeks

期刊介绍： Transactions of the Royal Society of Tropical Medicine and Hygiene publishes authoritative and impactful original, peer-reviewed articles and reviews on all aspects of tropical medicine.