The China national GeneBank sequence archive (CNSA) 2024 update

IF 8.7 1区农林科学 Q1 Agricultural and Biological Sciences

Horticulture Research Pub Date : 2025-02-04 DOI:10.1093/hr/uhaf036

Weiwen Wang, Cong Tan, Ling Li, Xia Li, Lei Zhang, Xiaoqiang Li, Jieyu Wang, Ziyi He, Tao Yang, Kailong Ma, Qingjiang Hu, Wenzhen Yang, Zhiyong Li, Mingwen Zhang, Wensi Du, Fan Yang, Zhicheng Xu, Xizheng Ma, Jiawei Tong, Jia Cai, Cong Hua, Fengzhen Chen, Lijin You, Liang Li, Wenjun Zeng, Bo Wang, Xun Xu, Xiaofeng Wei

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引用次数: 0

Abstract

The China National GeneBank Sequence Archive (CNSA) is an open and freely accessible curated data repository built for archiving, sharing, and re-utilizing of multi-omics data. The remarkable advancement in sequencing technologies has triggered a paradigm shift in life science research. However, it also poses tremendous challenges for the research community in data manage and reusability. With the dramatic advance of sequencing technologies like spatial transcriptome sequencing, it brings an unprecedented explosion in sequence data and new requirements for data archiving. CNSA was established in 2017 as one of the fundamental infrastructures to offer multi-omics data archiving for the worldwide research community. Here, we present the state-of-the-art enhancements of CNSA encompassing the dramatical increase of varied types of data, the latest features and services implemented in CNSA as well as consistent efforts supporting global cooperation in biodiversity preservation and utilization. CNSA provides public archiving and open-sharing services for sequencing data and relevant metadata including genome, transcriptome, metabolism, and proteome from single-cell (also spatial resolved) level to individual and population level, as well as further analyzed results. As of 2024, CNSA has archived over 16.3 petabytes of data and provided the data curation, preservation, and open-share service for over 1,581 publications from over 560 institutions. It plays a pivotal role in supporting global scientific projects such as the 10,000 Plant Genomes Project. So far, CNSA has been recommended by various academic publishers such as Cell, Elsevier, and Oxford University Press. CNSA is accessible at https://db.cngb.org/cnsa/.

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中国国家基因库序列档案（CNSA） 2024年更新

中国国家基因库序列档案（CNSA）是一个开放、免费访问的数据库，用于多组学数据的归档、共享和再利用。测序技术的显著进步引发了生命科学研究的范式转变。然而，它也给研究界在数据管理和可重用性方面提出了巨大的挑战。随着空间转录组测序等测序技术的迅猛发展，带来了前所未有的序列数据爆炸式增长，对数据存档提出了新的要求。CNSA成立于2017年，是为全球研究界提供多组学数据存档的基础设施之一。在此，我们介绍了CNSA的最新改进，包括各种类型数据的急剧增加，CNSA实施的最新功能和服务，以及支持生物多样性保护和利用的全球合作的持续努力。CNSA提供测序数据和相关元数据的公共存档和开放共享服务，包括基因组、转录组、代谢和蛋白质组，从单细胞（也包括空间分辨率）水平到个体和群体水平，以及进一步分析的结果。截至2024年，CNSA已存档数据超过16.3 pb，并为560多个机构的1581多种出版物提供数据管理、保存和开放共享服务。它在支持全球科学项目（如10,000株植物基因组计划）方面发挥着关键作用。到目前为止，CNSA已被各种学术出版商推荐，如Cell， Elsevier和牛津大学出版社。访问CNSA的网址是https://db.cngb.org/cnsa/。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Horticulture Research Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

11.20

自引率

6.90%

发文量

367

审稿时长

20 weeks

期刊介绍： Horticulture Research, an open access journal affiliated with Nanjing Agricultural University, has achieved the prestigious ranking of number one in the Horticulture category of the Journal Citation Reports ™ from Clarivate, 2022. As a leading publication in the field, the journal is dedicated to disseminating original research articles, comprehensive reviews, insightful perspectives, thought-provoking comments, and valuable correspondence articles and letters to the editor. Its scope encompasses all vital aspects of horticultural plants and disciplines, such as biotechnology, breeding, cellular and molecular biology, evolution, genetics, inter-species interactions, physiology, and the origination and domestication of crops.