Can Spinal Cord Stimulation be Considered as a Frontier for Chronic Pain in Diabetic Foot?

IF 4.1 2区 医学 Q1 CLINICAL NEUROLOGY
Pain and Therapy Pub Date : 2025-04-01 Epub Date: 2025-02-05 DOI:10.1007/s40122-025-00710-0
Ying Zhang, Huifeng Zhang, Kaizhong Wang, Xiangyan Liu, Zhonghai Li
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引用次数: 0

Abstract

Chronic pain in the diabetic foot (DF) is a common complication of diabetes, bringing a significant burden to patients, their families, and even society. There is no very effective treatment for it, traditional treatments such as medication, lumbar sympathetic nerve block, and alternative therapies are often not very effective and have more adverse effects. The emergence of neuromodulation technology has brought new hope for the treatment of DF, among which spinal cord stimulation (SCS) is a hotspot in current research and has achieved remarkable efficacy in the study of DF treatment by blocking pain signaling and improving circulation and other mechanisms. This article reviews the SCS technique and clinical trails of SCS for chronic DF pain, and describes the prospects and current challenges of SCS.

脊髓刺激可以作为治疗糖尿病足慢性疼痛的前沿疗法吗?
糖尿病足慢性疼痛是糖尿病的一种常见并发症,给患者、家属甚至社会带来了沉重的负担。目前并没有非常有效的治疗方法,传统的治疗方法如药物治疗、腰交感神经阻滞、替代疗法等往往效果不太好,而且副作用更大。神经调节技术的出现为DF的治疗带来了新的希望,其中脊髓刺激(spinal cord stimulation, SCS)是目前研究的热点,通过阻断疼痛信号、改善循环等机制对DF治疗的研究取得了显著的效果。本文综述了神经刺激技术和神经刺激治疗慢性DF疼痛的临床研究进展,并介绍了神经刺激治疗的前景和目前面临的挑战。
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来源期刊
Pain and Therapy
Pain and Therapy CLINICAL NEUROLOGY-
CiteScore
6.60
自引率
5.00%
发文量
110
审稿时长
6 weeks
期刊介绍: Pain and Therapy is an international, open access, peer-reviewed, rapid publication journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of pain therapies and pain-related devices. Studies relating to diagnosis, pharmacoeconomics, public health, quality of life, and patient care, management, and education are also encouraged. Areas of focus include, but are not limited to, acute pain, cancer pain, chronic pain, headache and migraine, neuropathic pain, opioids, palliative care and pain ethics, peri- and post-operative pain as well as rheumatic pain and fibromyalgia. The journal is of interest to a broad audience of pharmaceutical and healthcare professionals and publishes original research, reviews, case reports, trial protocols, short communications such as commentaries and editorials, and letters. The journal is read by a global audience and receives submissions from around the world. Pain and Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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