Bulky N-heterocyclic carbene Cu(I) complex as a catalyst for the synthesis of N-arylazoles under ambient conditions

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-01-05 DOI:10.1016/j.tet.2025.134449

Guiyan Liu , Qi Ding , Jiayi Chen , Ke Wang , Yongfei Zeng

引用次数: 0

Abstract

We reported a flexible copper complex modified with a bulky N-heterocyclic carbene (NHC) which was fully characterized. In addition, the catalytic activity of new NHC–Cu(I) complex for N-arylation reactions of N-heterocycles were investigated. The stable structure endowed the complex with efficient catalytic performance. As a catalyst, it could smoothly and effectively catalyze the N-arylation reactions of various N-heterocycles to produce N-arylazoles under mild conditions (60 °C) with a low catalyst loading (1 mol%).

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.