PANX1 hexamers work but cells prefer heptamers.

IF 3.3 2区医学 Q1 PHYSIOLOGY

Journal of General Physiology Pub Date : 2025-03-03 Epub Date: 2025-02-05 DOI:10.1085/jgp.202413727

Andrew L Harris

引用次数: 0

Abstract

Gupta et al. (https://doi.org/10.1085/jgp.202413676) reconcile a disconnect between structural and functional data regarding stoichiometry of PANX1 channels and provide new insights about channel activation.

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PANX1 六聚体可以工作，但细胞更喜欢七聚体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of General Physiology 医学-生理学

CiteScore

6.00

自引率

10.50%

发文量

审稿时长

6-12 weeks

期刊介绍： General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization. The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.