Observed vs. Expected organs transplanted in pediatric donors at Saint Francis hospital

Q4 Medicine
R. Goodwin , K. Champlin , B. Cloud , C. Yancey , C. Hendrix , S. Parikh , M. Howell , R. Ketcham , A. Milam , B. Nave , T. Campbell , M. Cheruvu
{"title":"Observed vs. Expected organs transplanted in pediatric donors at Saint Francis hospital","authors":"R. Goodwin ,&nbsp;K. Champlin ,&nbsp;B. Cloud ,&nbsp;C. Yancey ,&nbsp;C. Hendrix ,&nbsp;S. Parikh ,&nbsp;M. Howell ,&nbsp;R. Ketcham ,&nbsp;A. Milam ,&nbsp;B. Nave ,&nbsp;T. Campbell ,&nbsp;M. Cheruvu","doi":"10.1016/j.tpr.2024.100169","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>This retrospective case study aims to clarify the roles played by various factors in determining the actual versus expected number of organs procured from pediatric trauma patients.</div></div><div><h3>Significance</h3><div>Trauma patients often have injuries so extensive that there is no hope of recovery. However, if they are stabilized, they may be able to save lives through organ donation. The more organs are procured, the more lives may be saved.</div></div><div><h3>Strategy and Implementation</h3><div>In this retrospective study, we reviewed the records of pediatric organ donors from Saint Francis Children's Hospital from 2018 to 2022 and identified seven interesting cases involving children younger than 15 years old that showed the actual and expected numbers of organs transplanted. We examined the number of organs that we expected to transplant compared with how many organs were actually transplanted and which clinical data may have affected the ability to transplant.</div></div><div><h3>Outcomes</h3><div>The data analysis included but was not limited to the observed-to-expected ratio, donor management goals, hospital lab and biometric values before the time of referral, cause of death, age, sex, race, body mass index, blood type, kidney donor profile index, referral timeliness, donation conversations, donation conversation outcomes, hospital attending, pre-mentions of donation to potential families, referral and donation milestone date-time stamps, donor outcomes, organs recovered, organs transplanted, organs discarded, organs submitted to research, and survey responses. Based on the seven identified cases, this study shows that an observed-to-expected ratio greater than 1 is achievable.</div></div><div><h3>Implications for Practice</h3><div>Identifying factors that affect increased observed organ procurement will increase the potential of transplantable organs, thus leading to a higher number of lives saved.</div></div>","PeriodicalId":37786,"journal":{"name":"Transplantation Reports","volume":"10 1","pages":"Article 100169"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transplantation Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2451959624000209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose

This retrospective case study aims to clarify the roles played by various factors in determining the actual versus expected number of organs procured from pediatric trauma patients.

Significance

Trauma patients often have injuries so extensive that there is no hope of recovery. However, if they are stabilized, they may be able to save lives through organ donation. The more organs are procured, the more lives may be saved.

Strategy and Implementation

In this retrospective study, we reviewed the records of pediatric organ donors from Saint Francis Children's Hospital from 2018 to 2022 and identified seven interesting cases involving children younger than 15 years old that showed the actual and expected numbers of organs transplanted. We examined the number of organs that we expected to transplant compared with how many organs were actually transplanted and which clinical data may have affected the ability to transplant.

Outcomes

The data analysis included but was not limited to the observed-to-expected ratio, donor management goals, hospital lab and biometric values before the time of referral, cause of death, age, sex, race, body mass index, blood type, kidney donor profile index, referral timeliness, donation conversations, donation conversation outcomes, hospital attending, pre-mentions of donation to potential families, referral and donation milestone date-time stamps, donor outcomes, organs recovered, organs transplanted, organs discarded, organs submitted to research, and survey responses. Based on the seven identified cases, this study shows that an observed-to-expected ratio greater than 1 is achievable.

Implications for Practice

Identifying factors that affect increased observed organ procurement will increase the potential of transplantable organs, thus leading to a higher number of lives saved.
圣弗朗西斯医院儿童供体观察到的与预期的器官移植
目的:本回顾性病例研究旨在阐明各种因素在决定从儿童创伤患者获得的实际器官数量与预期器官数量之间的作用。意义创伤患者的损伤通常非常大,以至于没有康复的希望。然而,如果病情稳定下来,他们可能会通过器官捐赠来挽救生命。获得的器官越多,就能挽救越多的生命。策略与实施在这项回顾性研究中,我们回顾了圣弗朗西斯儿童医院2018年至2022年的儿童器官捐赠者记录,并确定了7例涉及15岁以下儿童的有趣病例,这些病例显示了实际和预期的器官移植数量。我们检查了我们期望移植的器官数量与实际移植的器官数量以及哪些临床数据可能影响移植能力。数据分析包括但不限于:观察预期比、献血者管理目标、转诊前的医院实验室和生物特征值、死亡原因、年龄、性别、种族、体重指数、血型、肾脏献血者概况指数、转诊及时性、捐赠谈话、捐赠谈话结果、医院就诊、向潜在家庭预先提及捐赠、转诊和捐赠里程碑日期-时间标记、献血者结果、器官恢复、移植的器官,丢弃的器官,用于研究的器官,以及调查结果。基于所确定的七个案例,本研究表明,观察到的期望比大于1是可以实现的。对实践的影响识别影响观察到的器官获取增加的因素将增加可移植器官的潜力,从而导致更多的生命得到挽救。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信