New dimeric 1,3-dihydroisobenzofuran from culture broth of Fennellia flavipes

IF 1.3 4区生物学 Q4 CHEMISTRY, MEDICINAL

Phytochemistry Letters Pub Date : 2025-02-01 DOI:10.1016/j.phytol.2025.01.003

Dae-Cheol Choi , Dae-Won Ki , Ji-Yul Kim , In-Kyoung Lee , Bong-Sik Yun

引用次数: 0

Abstract

A new dimeric 1,3-dihydroisobenzofuran, flavibenzofuran A (1), together with five known compounds, 1,3-dihydro-5-methoxy-7-methylisobenzofuran (2), epicoccin (3), 3-methoxyepicoccone B (4), sulochrin (5), and dihydrogeodin (6), were isolated from the culture broth of Fennellia flavipes. Their chemical structures were determined based on various spectroscopic methods and comparing their spectroscopic data with those reported in the literature. These compounds exhibited potent free radical scavenging activities against ABTS and DPPH radicals.

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茴香培养液中新的二聚体1,3-二氢异苯并呋喃

从茴香的培养液中分离到新的二聚体1,3-二氢异苯并呋喃黄酮A(1)，以及已知的5个化合物1,3-二氢-5-甲氧基-7-甲基异苯并呋喃(2)、表星素(3)、3-甲氧基皮occone B(4)、苏洛林(5)和二氢土豆素(6)。利用各种光谱方法测定了它们的化学结构，并与文献报道的光谱数据进行了比较。这些化合物对ABTS和DPPH自由基具有较强的清除活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Phytochemistry Letters 生物-生化与分子生物学

CiteScore

3.00

自引率

11.80%

发文量

190

审稿时长

34 days

期刊介绍： Phytochemistry Letters invites rapid communications on all aspects of natural product research including: • Structural elucidation of natural products • Analytical evaluation of herbal medicines • Clinical efficacy, safety and pharmacovigilance of herbal medicines • Natural product biosynthesis • Natural product synthesis and chemical modification • Natural product metabolism • Chemical ecology • Biotechnology • Bioassay-guided isolation • Pharmacognosy • Pharmacology of natural products • Metabolomics • Ethnobotany and traditional usage • Genetics of natural products Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.