A comprehensive review on roles of electrochemical approaches in drug delivery

IF 5.4 Q1 CHEMISTRY, ANALYTICAL

Sensing and Bio-Sensing Research Pub Date : 2025-02-01 DOI:10.1016/j.sbsr.2025.100742

Ali R. Jalalvand, Mohammad Mehdi Karami

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引用次数: 0

Abstract

The advancement of drug delivery systems (DDS) has significantly enhanced the efficacy and safety of therapeutic agents addressing limitations such as poor bioavailability and non-specific distribution associated with traditional methods. This article provides a comprehensive review of the role of electrochemical approaches in DDS, highlighting their precision, minimally invasive nature and ability to provide targeted and localized therapy. Electrochemical methods including voltammetry, amperometry and potentiometry offer unparalleled control over drug release kinetics and distribution, presenting significant advantages for the treatment of chronic and complex diseases like cancer, cardiovascular disorders, and neurological conditions. The integration of biotechnology, materials science and nanotechnology has led to the development of sophisticated DDS that respond to specific biological signals. This review discusses the fundamental principles of electrochemistry, various electrochemical techniques, and their applications in DDS alongside current innovations and future research directions in the field. The potential of electrochemical approaches to revolutionize drug delivery by providing precise, controlled, and targeted therapeutic interventions is emphasized, underscoring their growing importance in personalized medicine and future biomedical applications.

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来源期刊

Sensing and Bio-Sensing Research Engineering-Electrical and Electronic Engineering

CiteScore

10.70

自引率

3.80%

发文量

审稿时长

87 days

期刊介绍： Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies. The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.