Simulation of bioresorption of polymer matrixes for regenerative medicine

Abstract

The creation of modern biocompatible polymer structures with valuable functional properties based on biodegradable polymers allows us to propose new approaches to obtaining innovative materials to solve biomedical problems. However, the problem of choosing the optimal polymer matrices for regenerative medicine is acute. The work is aimed at expanding the boundaries of ideas about the modeling of bioresorption in various media and the role of supramolecular structure in these processes. Based on the DSC and GPС methods, it is possible to assess the contribution of the supramolecular structure of the polymer, in particular the degree of crystallinity and the state of the amorphous phase in bioresorption in a living organism and in a model environment.