Ayushmaan Roy , Mohammad Adnan Raza , Vijayalakshmi Ghosh , Ajazuddin
{"title":"Diagnostic innovations and therapeutic potential of nanoparticulate delivery for colon cancer","authors":"Ayushmaan Roy , Mohammad Adnan Raza , Vijayalakshmi Ghosh , Ajazuddin","doi":"10.1016/j.nanoso.2024.101426","DOIUrl":null,"url":null,"abstract":"<div><div>Colorectal cancer (CRC) is a frequently occurring malignant disease that affects people worldwide, especially those who are 50 years old or older and have a higher chance of developing the disease. Although improvements in diagnostic techniques and early screening have led to a decrease in cancer-related deaths, there remains an urgent want for novel treatment approaches. Scientists are quickly acknowledging the importance of nanoparticles (NPs) in improving the accuracy, effectiveness, and availability of diagnostic and treatments by enhancing the precision, solubility, and accessibility of pharmaceuticals. Nanoparticles (NPs) show potential in reducing medication toxicity and specifically targeting malignant tumors, therefore decreasing adverse side effects. This study comprehensively evaluates the practicality of using various nano products to detect and treat colorectal cancer (CRC). This study adds to the paradigm change in CRC management by conducting a thorough analysis of the potential of NPs. Incorporating cutting-edge nanotechnologies into CRC treatments can bring about significant changes, providing a way to develop individualized and precise therapies. This analysis highlights the need to use new and creative methods to satisfy the ongoing requirement for advanced therapies in light of the worldwide effect of colorectal cancer (CRC). With the increasing need for effective treatments, investigating nanoproducts becomes a new area of study with significant implications for CRC management. This highlights the need for ongoing research and development in this rapidly evolving sector.</div></div>","PeriodicalId":397,"journal":{"name":"Nano-Structures & Nano-Objects","volume":"41 ","pages":"Article 101426"},"PeriodicalIF":5.4500,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nano-Structures & Nano-Objects","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352507X2400338X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Physics and Astronomy","Score":null,"Total":0}
引用次数: 0
Abstract
Colorectal cancer (CRC) is a frequently occurring malignant disease that affects people worldwide, especially those who are 50 years old or older and have a higher chance of developing the disease. Although improvements in diagnostic techniques and early screening have led to a decrease in cancer-related deaths, there remains an urgent want for novel treatment approaches. Scientists are quickly acknowledging the importance of nanoparticles (NPs) in improving the accuracy, effectiveness, and availability of diagnostic and treatments by enhancing the precision, solubility, and accessibility of pharmaceuticals. Nanoparticles (NPs) show potential in reducing medication toxicity and specifically targeting malignant tumors, therefore decreasing adverse side effects. This study comprehensively evaluates the practicality of using various nano products to detect and treat colorectal cancer (CRC). This study adds to the paradigm change in CRC management by conducting a thorough analysis of the potential of NPs. Incorporating cutting-edge nanotechnologies into CRC treatments can bring about significant changes, providing a way to develop individualized and precise therapies. This analysis highlights the need to use new and creative methods to satisfy the ongoing requirement for advanced therapies in light of the worldwide effect of colorectal cancer (CRC). With the increasing need for effective treatments, investigating nanoproducts becomes a new area of study with significant implications for CRC management. This highlights the need for ongoing research and development in this rapidly evolving sector.
期刊介绍:
Nano-Structures & Nano-Objects is a new journal devoted to all aspects of the synthesis and the properties of this new flourishing domain. The journal is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. The journal is focused on the objects rather than on their applications. However, the research for new applications of original nano-structures & nano-objects in various fields such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine is also welcome. The scope of Nano-Structures & Nano-Objects involves: -Metal and alloy nanoparticles with complex nanostructures such as shape control, core-shell and dumbells -Oxide nanoparticles and nanostructures, with complex oxide/metal, oxide/surface and oxide /organic interfaces -Inorganic semi-conducting nanoparticles (quantum dots) with an emphasis on new phases, structures, shapes and complexity -Nanostructures involving molecular inorganic species such as nanoparticles of coordination compounds, molecular magnets, spin transition nanoparticles etc. or organic nano-objects, in particular for molecular electronics -Nanostructured materials such as nano-MOFs and nano-zeolites -Hetero-junctions between molecules and nano-objects, between different nano-objects & nanostructures or between nano-objects & nanostructures and surfaces -Methods of characterization specific of the nano size or adapted for the nano size such as X-ray and neutron scattering, light scattering, NMR, Raman, Plasmonics, near field microscopies, various TEM and SEM techniques, magnetic studies, etc .