Advancing lipid nanoparticles: A pioneering technology in cosmetic and dermatological treatments

IF 4.7 3区材料科学 Q2 CHEMISTRY, PHYSICAL

Colloid and Interface Science Communications Pub Date : 2025-01-01 DOI:10.1016/j.colcom.2024.100814

Anil Pareek , Devesh U. Kapoor , Sandeep Kumar Yadav , Summya Rashid , Mohammad Fareed , Mohammad Suhail Akhter , Ghazala Muteeb , Madan Mohan Gupta , Bhupendra G. Prajapati

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Abstract

Lipid nanoparticles (LNPs) represent a groundbreaking advancement in the realms of cosmetics and dermatology, providing advantages over traditional formulations. This paper explores the revolutionary potential of LNPs, particularly Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs), in enhancing cosmetic and dermatological applications. The review highlights the advantages of LNPs, including improved skin penetration, improved bioavailability and controlled release of active ingredients, which together contribute to their superior performance compared to conventional formulations. Notable applications discussed include their roles in acne treatment, anti-aging solutions, wound healing, skin-lightening products, and sunscreens. This study examines the structural features and formulation techniques of LNPs, highlighting biocompatibility, and targeted delivery capabilities. We also explore emerging uses such as genetic medicine and mRNA vaccine delivery, alongside market trends and consumer acceptance. By summarizing recent developments and identifying existing challenges, this paper offers a thorough overview of LNPs for future research in pharmaceutical and cosmetic advancements.

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推进脂质纳米颗粒：美容和皮肤治疗的先驱技术

脂质纳米颗粒（LNPs）代表了化妆品和皮肤病学领域的突破性进步，提供了传统配方的优势。本文探讨了LNPs的革命性潜力，特别是固体脂质纳米颗粒（sln）和纳米结构脂质载体（NLCs），在增强化妆品和皮肤病学应用方面。这篇综述强调了LNPs的优点，包括改善皮肤渗透，提高生物利用度和控制活性成分的释放，这些共同促进了它们与传统配方相比的优越性能。值得注意的应用包括它们在痤疮治疗、抗衰老解决方案、伤口愈合、美白产品和防晒霜中的作用。本研究考察了LNPs的结构特征和配方技术，强调了生物相容性和靶向递送能力。除了市场趋势和消费者接受程度外，我们还探讨了遗传医学和mRNA疫苗递送等新兴用途。通过总结最近的发展和确定存在的挑战，本文提供了LNPs的全面概述，为未来的研究在制药和化妆品的进步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colloid and Interface Science Communications Materials Science-Materials Chemistry

CiteScore

9.40

自引率

6.70%

发文量

125

审稿时长

43 days

期刊介绍： Colloid and Interface Science Communications provides a forum for the highest visibility and rapid publication of short initial reports on new fundamental concepts, research findings, and topical applications at the forefront of the increasingly interdisciplinary area of colloid and interface science.