Assessment of the quality of life of patients with inflammatory bowel disease

María del Mar Calvo Bernal , Elena Pérez Campos , Adrián Aparicio Mota , Álvaro Hernández Martínez
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Abstract

Introduction

Ulcerative colitis (UC) and Crohn's disease (CD) are diseases that cause a significant impact on patients' quality of life.
The aim of this study is to assess the impact of inflammatory bowel disease (IBD) on health-related quality of life (HRQoL).

Material and methods

Observational, descriptive, cross-sectional study, carried out at Torrecárdenas Hospital (Almería). Patients over 14 years of age diagnosed with CD or UC were included. For the assessment of HRQoL, the reduced 9-item IBDQ-9 questionnaire was used.

Results

106 patients with a mean age of 44 years were included, with a female predominance. Forty-five percent of the patients in the sample had UC compared to 55% with CD. Of the patients, 69.8% were in clinical remission. The median questionnaire score was 60.8 points out of 100. Statistically significant differences were observed between sexes, with worse HRQoL for females. No differences were observed between patients with UC and CD. Differences were also detected between patients who underwent surgery and those who did not. A negative association was observed between the number of flares and the questionnaire score.

Conclusions

In our study population, there is an acceptable HRQoL, with no differences observed between CD and UC. Female sex, absence of clinical remission, number of previous outbreaks, and surgery have a negative association with HRQoL.
炎症性肠病患者的生活质量评估
溃疡性结肠炎(UC)和克罗恩病(CD)是对患者生活质量造成重大影响的疾病。本研究的目的是评估炎症性肠病(IBD)对健康相关生活质量(HRQoL)的影响。材料和方法观察性、描述性、横断面研究,在Torrecárdenas医院(Almería)进行。14岁以上诊断为乳糜泻或UC的患者被纳入研究。HRQoL的评定采用精简的IBDQ-9问卷。结果106例患者入组,平均年龄44岁,以女性为主。样本中45%的患者患有UC,而55%的患者患有CD。其中69.8%的患者临床缓解。问卷得分中位数为60.8分(满分100分)。性别差异有统计学意义,女性HRQoL较差。UC和CD患者之间没有观察到差异。在接受手术和未接受手术的患者之间也发现了差异。在耀斑次数与问卷得分之间观察到负相关。结论在我们的研究人群中,有一个可接受的HRQoL, CD和UC之间没有差异。女性、没有临床缓解、以前爆发的次数和手术与HRQoL呈负相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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