Post-prostatectomy radiation therapy: Updated guidelines of the Australian and New Zealand Radiation Oncology Genito-Urinary Group (FROGG)

IF 4.9 1区医学 Q1 ONCOLOGY

Radiotherapy and Oncology Pub Date : 2024-12-25 DOI:10.1016/j.radonc.2024.110690

Matthew Warrender-Sparkes , Jonathan M. Tomaszewski , Christopher Ip , Sarat Chander , David Christie , Niall M. Corcoran , Louise Emmett , Renee Finnigan , Amy Hayden , Braden Higgs , Patrick Horsley , Tanya Holt , Giuseppe Sasso , Thomas P. Shakespeare , Mark Sidhom , Alison Tree , Andrew Kneebone

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Abstract

Over the past few years, a number of randomised controlled trials have been published addressing the management of patients with biochemical recurrence of prostate cancer post-prostatectomy. The trials sought to answer crucial questions regarding the optimal timing, prescribed dose and fractionation of post-prostatectomy radiation therapy (PPRT), as well as identifying the role for androgen deprivation (ADT) and elective pelvic lymph node irradiation. At the same time the use of novel imaging techniques such as PSMA-PET-CT scan and multi-parametric MRI of the pelvis, has increased. The Australian and New Zealand Faculty of Radiation Oncology Genito-Urinary Group (FROGG) convened a conference in September 2022 to review the latest literature and update its recommendations. This conference was attended by Australian, New Zealand and International delegates with presentations being delivered by key opinion leaders in urology, radiation oncology, medical oncology, radiation therapy and diagnostic imaging. Unresolved issues were reviewed by the FROGG working party until consensus was reached. These recommendations cover the role of PPRT, ADT and elective pelvic lymph node irradiation. Technical aspects of radiation therapy, such as clinical target volume definitions and planning techniques, which have been in place since 2008, were also updated.

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来源期刊

Radiotherapy and Oncology 医学-核医学

CiteScore

10.30

自引率

10.50%

发文量

2445

审稿时长

45 days

期刊介绍： Radiotherapy and Oncology publishes papers describing original research as well as review articles. It covers areas of interest relating to radiation oncology. This includes: clinical radiotherapy, combined modality treatment, translational studies, epidemiological outcomes, imaging, dosimetry, and radiation therapy planning, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as data science in radiation oncology and physics aspects relevant to oncology.Papers on more general aspects of interest to the radiation oncologist including chemotherapy, surgery and immunology are also published.