Diagnostic imaging challenges of mammary Paget's disease presenting with subtle clinical and imaging features: A case report

Abstract

Mamary Paget's disease presents with subtle and insidious symptoms leading to late diagnosis that poses medical challenges. This uncommon pathology often has underlying ductal breast cancer, including in situ or invasive breast cancer, which makes early recognition crucial for better prognoses. A 78-year-old postmenopausal woman presented with progressive and persistent eczematous skin lesions of the nipple without breast lumps. Additional imaging procedures revealed subtle findings, but the histopathology and immunohistopathology confirmed Paget's disease. This case highlights the importance of the correlation between clinical findings and the chosen diagnostic method for establishing a definitive diagnosis of mammary Paget's disease.