Aliasghar Fakhri-Demeshghieh, Hamideh Hasannejad, Parniyan Khoramian, Vahid Rahmanian, Alireza Bahonar
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引用次数: 0
Abstract
Background: Avian colibacillosis are infections caused by Avian Pathogenic Escherichia coli which causes high morbidity, high mortality, and significant economic losses. Antibiotics such as tetracycline are an important treatment choice for colibacillosis in Iran. However, the irrational use of antibiotics has caused high antibiotic resistance. The aim of this study was to estimate the tetracycline resistance rate among E. coli isolates from broilers in Iran.
Methods: PubMed, Scopus, Web of Science, Google Scholar, Islamic World Science Citation, Scientific Information Database, and MagIran databases were searched from 2013 and 2023. Risk of bias assessment was assessed with Appraisal tool for Cross-Sectional Studies. For meta-analysis, a random effects model with Freeman-Tukey double arcsine transformation was used. Subgroup analysis for the year of publication and sensitivity analysis to assess the influence of individual studies were conducted and a province-level map of point estimates was drawn.
Results: Among 13 included studies, the pooled tetracycline resistance was 85% (95% CI: 76-92%) and I-squared was 94.29%. In subgroup analysis, resistance rate was higher for articles published in 2018-2023 (91%) compared to articles published in 2013-2017 (76%), but heterogeneity between groups was not statistically-significant (P=0.12). sensitivity analysis showed that the omission of individual studies caused no apparent change. The province-level map showed that most of the studies belonged to northern parts of Iran with Ardabil (99.65%) having the highest value.
Conclusion: Resistance against tetracycline in E. coli isolates from broilers in Iran is alarming. The sensible use of tetracycline is advised.
期刊介绍：
Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above mentioned research areas.
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