Theoretical Insights and Anticancer Potential of 2,6-Bis((E)-(2-amino-4-nitrophenylimino)methyl)-4-methoxyphenol and Its Binuclear Cu(II) Complex

IF 3.7 2区化学 Q2 CHEMISTRY, APPLIED

Applied Organometallic Chemistry Pub Date : 2025-01-19 DOI:10.1002/aoc.7984

S. Praveen, G. Parinamachivayam, P. Jeyaraman, R. Prabakarakrishnan, A. Natarajan, K. Geetha, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Arivalagan Pugazhendhi, Sabariswaran Kandasamy

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Abstract

This study explores the synthesis and applications of a new Schiff base, 2,6-bis((E)-(2-amino-4-nitrophenylimino)methyl)-4-methoxyphenol (HL), and its copper(II) complexes. The Schiff base was prepared by reacting 2-amino-4-nitroaniline with 2,6-diformyl-4-methoxyphenol and characterized using techniques like microanalysis, UV–Vis, IR spectroscopy, ¹H-NMR, and LC–MS, confirming its structure. Theoretical studies provided insights into its molecular geometry and electronic properties. Cyclic voltammetry of the copper complex revealed diffusion-controlled electrochemical behavior, involving a single-electron transfer. Both the Schiff base and its Cu(II) complexes exhibited promising anticorrosion and anticancer activities, highlighting their multifunctional potential in industrial and biomedical applications. This study emphasizes the importance of comprehensive characterization in developing innovative materials with practical uses.

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来源期刊

Applied Organometallic Chemistry 化学-无机化学与核化学

CiteScore

7.80

自引率

10.30%

发文量

408

审稿时长

2.2 months

期刊介绍： All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.