Acanthamoeba keratitis – conservative and surgical treatment

Abstract

Clinical signs of acanthamoeba keratitis are in early stages grey-dirty epithelium, pseudodendritiformic epitheliopathy, perineuritis, multifocal stromal infiltrates, ring infiltrate and in later stages scleritis, iris atrophy, anterior synechiae, secondary glaucoma, mature cataract, and chorioretinitis. Beside triple-topical-therapy, in therapy resistant cases surgical treatment options such as corneal cryotherapy, amniotic membrane transplantation, riboflavin-UVA crosslinking, and penetrating keratoplasty are applied.