Profiling Pro-Inflammatory Proteases as Biomolecular Signatures of Material-Induced Subcutaneous Host Response in Immuno-Competent Mice (Adv. Sci. 5/2025)

IF 14.3 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Nam M.P. Tran, Anh T.H. Truong, Dang T. Nguyen, Tram T. Dang
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Abstract

Proteases in Material-Induced Immune Response

Proteases play a crucial role in modulating inflammation, yet their influence on immune reactions to implanted materials is understudied. In article number 2309709, Nam Tran, Anh Truong, Dang Nguyen, and Tram Dang comprehensively profile protease responses to various microparticulate materials in immuno-competent mice, revealing a strong correlation between protease activity and expression of pro-inflammatory cytokines. The cover artwork captures how different materials trigger distinct levels of protease activity, measurable as a non-invasive biomolecular signature of material-induced immune response.

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来源期刊
Advanced Science
Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
18.90
自引率
2.60%
发文量
1602
审稿时长
1.9 months
期刊介绍: Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
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