Localized Hepatoblastoma in a Patient with Trisomy 18 Achieved Complete Remission with Radiation Therapy Alone

IF 6.4 1区医学 Q1 ONCOLOGY

International Journal of Radiation Oncology Biology Physics Pub Date : 2025-02-03 DOI:10.1016/j.ijrobp.2024.11.060

S. Chafe , M. Rojas , J. Zebak

引用次数: 0

Abstract

Objectives

Case report observing the response to palliative radiation therapy in a 19 month old with hepatoblastoma, Trisomy 18 and multiple comorbidities.

Methods

Radiation was delivered to the Liver mass. 3000 cGy was delivered in 10 daily fractions over 2 weeks.

Results

Complete resolution of the mass and AFP normalized by 4 months. The patient remains in remission 5 years post end of treatment.

Conclusion

Radiation should be a considered for patients with Hepatoblastoma who are not candidates for surgical resection and/or chemotherapy

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来源期刊

International Journal of Radiation Oncology Biology Physics 医学-核医学

CiteScore

11.00

自引率

7.10%

发文量

2538

审稿时长

6.6 weeks

期刊介绍： International Journal of Radiation Oncology • Biology • Physics (IJROBP), known in the field as the Red Journal, publishes original laboratory and clinical investigations related to radiation oncology, radiation biology, medical physics, and both education and health policy as it relates to the field. This journal has a particular interest in original contributions of the following types: prospective clinical trials, outcomes research, and large database interrogation. In addition, it seeks reports of high-impact innovations in single or combined modality treatment, tumor sensitization, normal tissue protection (including both precision avoidance and pharmacologic means), brachytherapy, particle irradiation, and cancer imaging. Technical advances related to dosimetry and conformal radiation treatment planning are of interest, as are basic science studies investigating tumor physiology and the molecular biology underlying cancer and normal tissue radiation response.