Enhanced magnetic hyperthermia performance in thermal plasma synthesized MnFe2O4 nanoparticles

IF 4.3 3区材料科学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Journal of Physics and Chemistry of Solids Pub Date : 2025-01-22 DOI:10.1016/j.jpcs.2025.112586

Kashmiri Deka , Gauri A. Deshpande , Shalaka A. Kamble , Vijaykumar B. Varma , R.V. Ramanujan , Priyanka Khot , Kisan M. Kodam , Som Datta Kaushik , P.D. Babu , Vikas L. Mathe

{"title":"Enhanced magnetic hyperthermia performance in thermal plasma synthesized MnFe2O4 nanoparticles","authors":"Kashmiri Deka , Gauri A. Deshpande , Shalaka A. Kamble , Vijaykumar B. Varma , R.V. Ramanujan , Priyanka Khot , Kisan M. Kodam , Som Datta Kaushik , P.D. Babu , Vikas L. Mathe","doi":"10.1016/j.jpcs.2025.112586","DOIUrl":null,"url":null,"abstract":"<div><div>Spherical manganese ferrite (MnFe<sub>2</sub>O<sub>4</sub>) nanoparticles (MFNPs) were synthesized by thermal plasma route for the first time. To check the efficiency of the developed MFNPs as magnetic hyperthermia agents, induction heating study was performed under an AC magnetic field (4 kA/m amplitude and 375 kHz frequency). The results demonstrated temperature increase to 50 °C within 2 s for bare MFNPs and 5 s for water dispersion of MFNPs. The specific absorption rate (SAR) of the MFNPs was found to be 403.78 Wg<sup>−1</sup> and 546.1 Wg<sup>−1</sup> using linear data fitting and Box-Lucas fitting methods respectively. These results were superior to those in the preceding reports using MFNPs as magnetic hyperthermia agents. Cytotoxicity assay on B16–F1 epithelial cells and A549 adenocarcinomic human alveolar basal epithelial cells proved high cell-viability of the synthesized MFNPs. Hence, our research demonstrated a thermal plasma-based synthesis of reproducible, and biocompatible MFNPs with superior performance which will improve accuracy and reduce side effects during targeted cancer treatment.</div></div>","PeriodicalId":16811,"journal":{"name":"Journal of Physics and Chemistry of Solids","volume":"200 ","pages":"Article 112586"},"PeriodicalIF":4.3000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Physics and Chemistry of Solids","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S002236972500037X","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Spherical manganese ferrite (MnFe₂O₄) nanoparticles (MFNPs) were synthesized by thermal plasma route for the first time. To check the efficiency of the developed MFNPs as magnetic hyperthermia agents, induction heating study was performed under an AC magnetic field (4 kA/m amplitude and 375 kHz frequency). The results demonstrated temperature increase to 50 °C within 2 s for bare MFNPs and 5 s for water dispersion of MFNPs. The specific absorption rate (SAR) of the MFNPs was found to be 403.78 Wg⁻¹ and 546.1 Wg⁻¹ using linear data fitting and Box-Lucas fitting methods respectively. These results were superior to those in the preceding reports using MFNPs as magnetic hyperthermia agents. Cytotoxicity assay on B16–F1 epithelial cells and A549 adenocarcinomic human alveolar basal epithelial cells proved high cell-viability of the synthesized MFNPs. Hence, our research demonstrated a thermal plasma-based synthesis of reproducible, and biocompatible MFNPs with superior performance which will improve accuracy and reduce side effects during targeted cancer treatment.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Physics and Chemistry of Solids 工程技术-化学综合

CiteScore

7.80

自引率

2.50%

发文量

605

审稿时长

40 days

期刊介绍： The Journal of Physics and Chemistry of Solids is a well-established international medium for publication of archival research in condensed matter and materials sciences. Areas of interest broadly include experimental and theoretical research on electronic, magnetic, spectroscopic and structural properties as well as the statistical mechanics and thermodynamics of materials. The focus is on gaining physical and chemical insight into the properties and potential applications of condensed matter systems. Within the broad scope of the journal, beyond regular contributions, the editors have identified submissions in the following areas of physics and chemistry of solids to be of special current interest to the journal: Low-dimensional systems Exotic states of quantum electron matter including topological phases Energy conversion and storage Interfaces, nanoparticles and catalysts.