Bowing Index in Individuals With Parkinson's Disease, Progressive Supranuclear Palsy, and Ataxia.

IF 2.2 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Laryngoscope Pub Date : 2025-02-02 DOI:10.1002/lary.31993

Courtney B Tipton, J C Borders, J A Curtis, M S Troche

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引用次数: 0

Abstract

Purpose: Variations in vocal fold bowing, as measured endoscopically with the bowing index (BI), across neurodegenerative diseases remain unexplored, which may inform interventions to minimize morbidity and mortality secondary to voice and airway protective dysfunction. The study's aim was to compare BI between people with Parkinson's disease, progressive supranuclear palsy, and cerebellar ataxia.

Methods: Thirty individuals with Parkinson's disease, 23 with progressive supranuclear palsy, and 24 with cerebellar ataxia were included and underwent flexible laryngoscopy. BI was measured using ImageJ software and a linear regression model was used to compare differences in total BI between groups, controlling for age.

Results: Average total BI was 14.60 (SD = 6.26, range 4.03-28.62) for people with progressive supranuclear palsy, 10.10 (SD = 6.64, range 0-34.13) for Parkinson's disease, and 8.35 (SD = 5.90, range 0-25.95) for cerebellar ataxia. Controlling for age, people with progressive supranuclear palsy demonstrated 4.74 greater BI compared to Parkinson's disease (95 CI: 1.19-8.28; p = 0.001), but there was no significant difference between people with Parkinson's disease and cerebellar ataxia (β = 0.37; 95% CI: -5.02, 5.77; p = 0.891) or people with progressive supranuclear palsy and cerebellar ataxia (β = 5.11; 95% CI: 0.01-10.21; p = 0.050).

Conclusions: The results suggest that BI is significantly greater in people with progressive supranuclear palsy compared to Parkinson's disease. It is important to recognize vocal fold atrophy and its potential impact on voice and airway protective measures in these patients.

Level of evidence: 3 Laryngoscope, 2025.

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来源期刊

Laryngoscope 医学-耳鼻喉科学

CiteScore

6.50

自引率

7.70%

发文量

500

审稿时长

2-4 weeks

期刊介绍： The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope. • Broncho-esophagology • Communicative disorders • Head and neck surgery • Plastic and reconstructive facial surgery • Oncology • Speech and hearing defects