Establishing Normative Values for Entire Spinal Cord Morphometrics in East Asian Young Adults.

IF 4.4 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Korean Journal of Radiology Pub Date : 2025-02-01 DOI:10.3348/kjr.2024.0907

Bio Joo, Hyung Jun Park, Mina Park, Sang Hyun Suh, Sung Jun Ahn

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引用次数: 0

Abstract

Objective: The quantitative assessment of spinal cord volume is still in the early stages of development. Recently, normative morphometric values of the cervical spinal cord have been reported. This study aimed to establish normative values for spinal cord morphometry, extending beyond the cervical region to include the thoracic and lumbar spinal cord, and to examine the influence of sex and ethnicity on these measurements.

Materials and methods: This prospective study included 28 young, healthy, East Asian volunteers (14 males and 14 females; mean age, 30.14 ± 4.07 years) who underwent spinal cord MRI using a 3T scanner. The cross-sectional areas (CSAs), anteroposterior (AP) and transverse diameters, and compression ratios of the entire spinal cord were calculated. Additionally, the effects of sex and ethnicity on spinal cord volumetry were evaluated, with the influence of ethnicity assessed by comparing the findings with a Caucasian dataset from the PAM50 study.

Results: The CSAs demonstrated two enlargements at the cervical and lumbar levels. The cervical enlargement at C4-5 exhibited an elliptical shape, while the lumbar enlargement at T12 appeared more circular. The CSAs and AP and transverse diameters of the spinal cords in males were significantly larger than that of females (P < 0.001). The spinal cord compression ratios in East Asians were significantly lower than those in Caucasians (P < 0.001).

Conclusion: This study revealed that the two spinal cord enlargements exhibit different patterns and suggest significant differences in spinal cord morphometric values according to sex and ethnicity.

查看原文本刊更多论文

建立东亚年轻人全脊髓形态计量学的规范值。

目的：脊髓体积的定量评估尚处于早期发展阶段。最近，颈脊髓的标准形态计量值已被报道。本研究旨在建立脊髓形态测量的规范值，从颈椎延伸到胸腰椎，并研究性别和种族对这些测量的影响。材料和方法：本前瞻性研究纳入了28名年轻、健康的东亚志愿者(14男14女；平均年龄30.14±4.07岁)，均行3T脊髓MRI检查。计算整个脊髓的横截面积（csa）、前后径（AP）和横径以及压缩比。此外，还评估了性别和种族对脊髓容量测定的影响，并通过将结果与PAM50研究中的高加索数据集进行比较来评估种族的影响。结果：csa显示颈椎和腰椎两处增大。C4-5的颈椎增大呈椭圆形，而T12的腰椎增大呈圆形。男性脊髓csa、AP及脊髓横径均显著大于女性（P < 0.001）。东亚人脊髓受压比显著低于白种人（P < 0.001）。结论：本研究揭示了两种脊髓增大表现出不同的模式，并提示脊髓形态学值在性别和种族方面存在显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Korean Journal of Radiology 医学-核医学

CiteScore

10.60

自引率

12.50%

发文量

141

审稿时长

1.3 months

期刊介绍： The inaugural issue of the Korean J Radiol came out in March 2000. Our journal aims to produce and propagate knowledge on radiologic imaging and related sciences. A unique feature of the articles published in the Journal will be their reflection of global trends in radiology combined with an East-Asian perspective. Geographic differences in disease prevalence will be reflected in the contents of papers, and this will serve to enrich our body of knowledge. World''s outstanding radiologists from many countries are serving as editorial board of our journal.