Unraveling the Mysteries: Paroxysmal Nocturnal Hemoglobinuria and Its Unexpected Link to Stroke in Young Adult.

Abstract

The increasing incidence of stroke among young adults challenges the conventional belief that strokes predominantly affect the elderly. This case report explores the complicated intersection of paroxysmal nocturnal hemoglobinuria (PNH) and strokes in young individuals, examining diagnostic challenges, underlying mechanisms, and the need to recognize this less-explored association for timely intervention. Here, we describe a case of a young male who presented to intensive care with a stroke against a background of recurrent thrombosis and was diagnosed with PNH. While conventional risk factors like hypertension and atherosclerosis are commonly associated with strokes, this case report sheds light on the less-explored connection between PNH and strokes in young adults, emphasizing the need to unravel these seemingly unrelated conditions for enhanced diagnostic precision and improved management.