Seasonal variation of unexpected sudden cardiac death in northern Finland

IF 2.3 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Pathology Pub Date : 2025-01-28 DOI:10.1016/j.carpath.2025.107725

Severi M Mattila , Hanna Latola , Lasse Pakanen , Jenni J Hekkanen , M Anette E Eskuri , Juha Vähätalo , Olavi H Ukkola , M Juhani Junttila , Heikki V Huikuri , Juha S Perkiömäki

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引用次数: 0

Abstract

Background

Data on the occurrence of unexpected sudden cardiac death (SCD) in different seasons are limited.

Methods

All unexpected sudden death victims have to undergo medico-legal autopsy obligated by the Finnish law. Consecutive series of all unexpected autopsied SCD victims (n = 5,869) were prospectively collected from the geographically defined area in the Northern Finland during a twenty years period from 1998 to 2017. We evaluated the seasonal variation of SCD and its possible causes.

Results

Unexpected SCD occurred more frequently during the first quarter of a year (from January to March) than during the other quarters. The occurrence of SCD during the twenty years follow-up was 4.5 ± 0.24 during the first quarter of the year per month and 3.9 ± 0.12 during the other quarters of the year per month on average (SCDs during the quarter of a year per month on average per 100,000 inhabitants per year, p < 0.001). The weather was colder during the first quarter of the year (average temperature -9.1 degrees centigrade) than during the other quarters (average temperature +5.7 degrees centigrade). The subjects who experienced SCD during the first quarter of the year had more commonly severe (75 %-90 %) coronary artery stenosis, (p < 0.001).

Conclusion

Unexpected SCD occurred more commonly during the first quarter of a year (from January to March) than during the other quarters (from April to December). Cold weather with its physiological consequences and more severe coronary artery disease predisposing to ischemia may have contributed to the increased occurrence of SCD during the first quarter of the year.

查看原文本刊更多论文

芬兰北部意外心源性猝死的季节变化。

背景：不同季节发生意外心源性猝死（SCD）的数据有限。方法：所有意外猝死的受害者都必须接受芬兰法律规定的法医尸检。在1998年至2017年的20年间，前瞻性地从芬兰北部地理上确定的区域收集了所有意外尸检的SCD受害者（n= 5869）的连续系列。我们评估了SCD的季节变化及其可能的原因。结果：1 - 3月第一季度意外SCD的发生频率高于其他季度。20年随访期间SCD的平均发生率为每年第一季度（4.5±0.24）例/月，其他季度（3.9±0.12）例/月（平均每10万人/年）。结论：每年第一季度（1 - 3月）意外SCD的发生率高于其他季度（4 - 12月）。寒冷的天气及其生理后果和更严重的冠状动脉疾病易导致缺血，可能是今年第一季度SCD发病率增加的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular Pathology 医学-病理学

CiteScore

7.50

自引率

2.70%

发文量

审稿时长

18 days

期刊介绍： Cardiovascular Pathology is a bimonthly journal that presents articles on topics covering the entire spectrum of cardiovascular disease. The Journal''s primary objective is to publish papers on disease-oriented morphology and pathogenesis from clinicians and scientists in the cardiovascular field. Subjects covered include cardiovascular biology, prosthetic devices, molecular biology and experimental models of cardiovascular disease.