mSphere of Influence: High-throughput screens to rapidly assign function to microbial genes.

IF 3.7 2区生物学 Q2 MICROBIOLOGY

mSphere Pub Date : 2025-02-25 Epub Date: 2025-01-29 DOI:10.1128/msphere.00800-24

Lori B Huberman

引用次数: 0

Abstract

Lori Huberman works in the field of fungal genetics, with an emphasis on investigating the genetic mechanisms fungi use to sense and respond to the nutrients and toxins in their environment. In this mSphere of Influence article, she reflects on how "Rapid quantification of mutant fitness in diverse bacteria by sequencing randomly bar-coded transposons" by K. M. Wetmore, M. N. Price, R. J. Waters, J. S. Lamson, et al. (mBio 6:e00306-15, 2015, https://doi.org/10.1128/mBio.00306-15) made an impact on her by establishing technologies that open realistic possibilities for developing high-throughput screening methods to correlate phenotype to genotype in diverse fungal species.

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来源期刊

mSphere Immunology and Microbiology-Microbiology

CiteScore

8.50

自引率

2.10%

发文量

192

审稿时长

11 weeks

期刊介绍： mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.