A branching model for intergenerational telomere length dynamics.

IF 2.2 4区数学 Q2 BIOLOGY

Journal of Mathematical Biology Pub Date : 2025-01-26 DOI:10.1007/s00285-025-02185-1

Athanasios Benetos, Olivier Coudray, Anne Gégout-Petit, Lionel Lenôtre, Simon Toupance, Denis Villemonais

引用次数: 0

Abstract

We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean telomere length and its age. We study its Malthusian's behaviour and provide numerical simulations to understand the influence of biologically relevant parameters.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Mathematical Biology 生物-生物学

CiteScore

3.30

自引率

5.30%

发文量

120

审稿时长

6 months

期刊介绍： The Journal of Mathematical Biology focuses on mathematical biology - work that uses mathematical approaches to gain biological understanding or explain biological phenomena. Areas of biology covered include, but are not restricted to, cell biology, physiology, development, neurobiology, genetics and population genetics, population biology, ecology, behavioural biology, evolution, epidemiology, immunology, molecular biology, biofluids, DNA and protein structure and function. All mathematical approaches including computational and visualization approaches are appropriate.