Application of fibrin sealant in drain-free transoral endoscopic thyroidectomy vestibular approach.

IF 1.4 Q2 MEDICINE, GENERAL & INTERNAL

Tzu Chi Medical Journal Pub Date : 2024-08-19 eCollection Date: 2025-01-01 DOI:10.4103/tcmj.tcmj_41_24

Wei-Chieh Lin, Ciou-Nan Ye, Chung-Ching Lin, Pornpeera Jitpratoom, Hung-Pin Wu, Yi-Fan Chou

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引用次数: 0

Abstract

Objective: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a minimally invasive technique. This study aimed to compare the safety of TOETVA with fibrin sealant (Tisseel) and TOETVA with drainage.

Materials and methods: Patients who underwent TOETVA between January 2018 and December 2021 were divided into drainage (n = 20) and Tisseel (n = 30) groups.

Results: The primary outcome was the incidence of complications. The secondary outcomes were operative time and postoperative pain. There were no significant differences in patient demographics, tumor size, intraoperative blood loss, and hospitalization days between the two groups. No patient required conversion to open thyroidectomy. The incidence of complications and postoperative pain was similar in the two groups. The operative time for TOETVA with Tisseel was significantly shorter than for TOETVA with drainage (P = 0.038).

Conclusion: TOETVA with Tisseel is a safe alternative to TOETVA with drainage, having a short operative time.

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纤维蛋白密封胶在经口内窥镜前庭入路甲状腺切除术中的应用。

目的：经口内窥镜前庭入路甲状腺切除术是一种微创手术。本研究旨在比较TOETVA与纤维蛋白密封剂（Tisseel）和TOETVA与引流的安全性。材料与方法：将2018年1月至2021年12月接受TOETVA手术的患者分为引流组（n = 20）和Tisseel组（n = 30）。结果：以并发症发生率为主要观察指标。次要结果为手术时间和术后疼痛。两组患者在人口统计学、肿瘤大小、术中出血量和住院天数方面无显著差异。没有患者需要转行开放性甲状腺切除术。两组患者并发症及术后疼痛发生率相似。Tisseel置换术的手术时间明显短于引流术（P = 0.038）。结论：Tisseel TOETVA联合引流是一种安全的替代TOETVA联合引流的方法，手术时间短。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tzu Chi Medical Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： The Tzu Chi Medical Journal is the peer-reviewed publication of the Buddhist Compassion Relief Tzu Chi Foundation, and includes original research papers on clinical medicine and basic science, case reports, clinical pathological pages, and review articles.