Comparing synthetic mammograms based on wide-angle digital breast tomosynthesis with digital mammograms.

IF 1.9 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging Pub Date : 2025-01-01 Epub Date: 2025-01-20 DOI:10.1117/1.JMI.12.S1.S13011

Magnus Dustler, Gustav Hellgren, Pontus Timberg

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引用次数: 0

Abstract

Purpose: We aim to investigate the characteristics and evaluate the performance of synthetic mammograms (SMs) based on wide-angle digital breast tomosynthesis (DBT) compared with digital mammography (DM).

Approach: Fifty cases with both synthetic and digital mammograms were selected from the Malmö Breast Tomosynthesis Screening Trial. They were categorized into five groups consisting of normal cases and recalled cases with false-positive and true-positive findings from DM and DBT only. The DBT system used was a wide-angle (WA) system from Siemens, and the SM images were reconstructed from the DBT images. Visual grading, detection, and recall were evaluated by experienced breast radiologists in both SM and DM images.

Results: Some image quality criteria of the SM images were rated as qualitatively inferior to DM images. However, reader-averaged diagnostic accuracy (0.57 versus 0.55), sensitivity (0.46 versus 0.50), and specificity (0.64 versus 0.58) were not significantly different between SM and DM, respectively.

Conclusions: Synthetic mammography plays a promising role to complement or even replace DM. The study could not find any indications of substantial differences in the sensitivity or specificity of SM for WA DBT systems compared with DM. However, certain image quality criteria of SM fall slightly short compared with DM images. Next-generation DBT systems could address such limitations through improved reconstruction algorithms and system design, and their performance should be the focus of future research studies.

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基于广角数字乳腺断层合成的合成乳房x线照片与数字乳房x线照片的比较。

目的：探讨基于广角数字乳腺断层合成（DBT）的合成乳房x线照片（SMs）的特点，并与数字乳房x线摄影（DM）进行比较。方法：从Malmö乳腺断层合成筛查试验中选择50例合成和数字乳房x线照片。他们被分为五组，包括正常病例和召回病例，假阳性和真阳性结果仅来自DM和DBT。使用的DBT系统是西门子公司的广角（WA）系统，从DBT图像重建SM图像。由经验丰富的乳腺放射科医生对SM和DM图像的视觉分级、检测和召回进行评估。结果：SM图像的一些质量指标被评为质量低于DM图像。然而，读者平均诊断准确率（0.57 vs 0.55）、敏感性（0.46 vs 0.50）和特异性（0.64 vs 0.58）在SM和DM之间分别没有显著差异。结论：综合乳房x线摄影在补充甚至替代DM方面具有很好的作用，本研究未发现任何迹象表明SM在WA DBT系统中的敏感性或特异性与DM相比有实质性差异，但SM的某些图像质量标准与DM图像相比略有不足。下一代DBT系统可以通过改进重建算法和系统设计来解决这些限制，其性能应该是未来研究的重点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.10

自引率

4.20%

发文量

期刊介绍： JMI covers fundamental and translational research, as well as applications, focused on medical imaging, which continue to yield physical and biomedical advancements in the early detection, diagnostics, and therapy of disease as well as in the understanding of normal. The scope of JMI includes: Imaging physics, Tomographic reconstruction algorithms (such as those in CT and MRI), Image processing and deep learning, Computer-aided diagnosis and quantitative image analysis, Visualization and modeling, Picture archiving and communications systems (PACS), Image perception and observer performance, Technology assessment, Ultrasonic imaging, Image-guided procedures, Digital pathology, Biomedical applications of biomedical imaging. JMI allows for the peer-reviewed communication and archiving of scientific developments, translational and clinical applications, reviews, and recommendations for the field.