Andrea Montis, Victoria Paredes-Orejudo, Axelle Bourez, Jack Steed, Piet Stoffelen, Cedric Delporte, Florence Souard, Jianru Stahl-Zeng, Pierre Van Antwerpen
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引用次数: 0
Abstract
Introduction: ZenoTOF is new class of high-resolution mass spectrometer that combines resolution and sensitivity. This mass spectrometer is well designed to perform metabolomics.
Methods: In this context, we compared the performance of ZenoTOF 7600 system (Sciex) with QTOF6520 (Agilent Technologies) through the leaf metabolome analysis of two Coffea species, namely C. anthonyi and C. arabica.
Results: Both species were used to compare both TOF systems. Our results showed that the ZenoTOF 7600 system provided more features (3146 vs 2326 metabolites) and more nodes (1410 vs 379 metabolites) by molecular network in only one injection.
Conclusion: These performances were attributed to the scan speed and sensitivity of the ZenotTOF and demonstrates its added value in the context of metabolomics.
期刊介绍：
Metabolomics publishes current research regarding the development of technology platforms for metabolomics. This includes, but is not limited to:
metabolomic applications within man, including pre-clinical and clinical
pharmacometabolomics for precision medicine
metabolic profiling and fingerprinting
metabolite target analysis
metabolomic applications within animals, plants and microbes
transcriptomics and proteomics in systems biology
Metabolomics is an indispensable platform for researchers using new post-genomics approaches, to discover networks and interactions between metabolites, pharmaceuticals, SNPs, proteins and more. Its articles go beyond the genome and metabolome, by including original clinical study material together with big data from new emerging technologies.
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