Paraneoplastic syndrome with intestinal pseudo-obstruction in a patient with small cell lung carcinoma: a case report and literature review.

IF 1.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Xiao-Jun Ren, Zhao-Hong Shi, Ying-Xia Cheng, Yun Luo
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引用次数: 0

Abstract

Paraneoplastic chronic intestinal pseudo-obstruction (CIPO) is a rare manifestation associated with small cell lung carcinoma and other malignancies. In this report, we present a challenging case involving a 60-year-old man with small cell lung carcinoma who developed symptoms of intestinal pseudo-obstruction, including abdominal distention, pain, and obstipation. Despite receiving extensive treatment with intravenous gamma globulin and glucocorticoids, the patient's symptoms did not improve, ultimately resulting in irreversible nervous system damage. Through a comprehensive literature review, we explore the underlying mechanisms of paraneoplastic CIPO and discuss its diagnostic and therapeutic approaches. We emphasize the significance of timely detection of related antibodies for early diagnosis and treatment of CIPO to improve patient outcomes.

小细胞肺癌伴假肠梗阻的副肿瘤综合征1例报告并文献复习。
摘要副肿瘤性慢性肠道假性梗阻(CIPO)是一种与小细胞肺癌及其他恶性肿瘤相关的罕见表现。在这个报告中,我们提出了一个具有挑战性的病例,涉及一名60岁的小细胞肺癌患者,他出现了肠道假性梗阻的症状,包括腹胀、疼痛和梗阻。尽管接受了广泛的静脉注射丙种球蛋白和糖皮质激素治疗,但患者的症状并没有改善,最终导致了不可逆转的神经系统损伤。通过全面的文献回顾,我们探讨了副肿瘤CIPO的潜在机制,并讨论了其诊断和治疗方法。我们强调及时检测相关抗体对CIPO早期诊断和治疗的重要性,以改善患者的预后。
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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
555
审稿时长
1 months
期刊介绍: _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605
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