Lymphocytic Gastritis in a Patient With Microscopic Colitis: A Case Report.

Abstract

Lymphocytic gastritis (LG) is a rare form of gastritis characterized by lymphocytosis in the gastric mucosa, while microscopic colitis (MC) is the chronic inflammatory disease of the large intestine with lymphocytic or collagenous colitis as two distinct histologic forms. These lymphocytic disorders of the gastrointestinal tract (GIT) have various associations, commonly gluten-sensitive enteropathy, Helicobacter pylori infection and while others are less commonly associated. We report a case of a 24-year-old patient with concomitant lymphocytic gastritis and microscopic colitis diagnosed via histopathologic analysis of tissue specimens from stomach and colon. The presence of a lymphocytic disorder in GIT should prompt workup for associated disorders. There is also an association between lymphocytic disorders of the lower GIT with the upper GIT, and vice versa. Endoscopy is important to diagnose comorbid lymphocytic conditions, and subsequently, guiding treatment.