Petroclival meningioma regression after combined oestrogen and nomegestrol acetate interruption.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

BMJ Case Reports Pub Date : 2025-01-19 DOI:10.1136/bcr-2024-263529

Julie Lebeau, Louis Deprez, Axelle Pintiaux, Gilles Reuter

引用次数: 0

Abstract

Meningioma regression after progestin treatment interruption is already established. Zoely is a combined oral contraceptive including oestradiol and progestin (nomegestrol acetate). The effect of combined oestrogen with nomegestrol acetate on meningioma is currently unknown. We report the case of a woman in her early 50s under Zoely for 5 years who was diagnosed with a large petroclival meningioma. After cessation of Zoely, the patient showed clinical improvement and shrinkage of the tumour volume from 27.22 cm³ to 20.54 cm³ in 6 months. This is probably the first report of spontaneous meningioma regression after Zoely interruption.

查看原文本刊更多论文

雌激素和醋酸异孕酮联合中断后岩斜坡脑膜瘤消退。

黄体酮治疗中断后脑膜瘤消退已经确定。Zoely是一种包括雌二醇和黄体酮（醋酸异孕酮）的联合口服避孕药。雌激素联合醋酸异孕酮治疗脑膜瘤的效果目前尚不清楚。我们报告的情况下，在她50岁出头的妇女下Zoely 5年谁被诊断为一个大岩斜坡脑膜瘤。停用Zoely后，患者临床改善，肿瘤体积在6个月内由27.22 cm3缩小至20.54 cm3。这可能是Zoely中断后自发性脑膜瘤消退的首次报道。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

BMJ Case Reports Medicine-Medicine (all)

CiteScore

1.40

自引率

0.00%

发文量

1588

期刊介绍： BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.