Rare Finding of Rectal Squamous Metaplasia in Inflammatory Bowel Disease.

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-01-17 eCollection Date: 2025-01-01 DOI:10.14309/crj.0000000000001598

Sangkyu Noh, Franklin Liu, Samuel H Cheong, Sasha Taleban

引用次数: 0

Abstract

Rectal squamous metaplasia in inflammatory bowel disease is rare. We present 2 cases of rectal squamous metaplasia, one in a patient with Crohn's disease and another with ulcerative colitis. Given the risk of malignant transformation, dysplasia surveillance is important particularly in areas of chronic inflammation. Furthermore, human papilloma virus (HPV) is involved in the pathogenesis of anal squamous cell carcinoma (SCC), but no guidelines exist in the United States for HPV prophylaxis against anal SCC in inflammatory bowel disease. HPV vaccination should be considered in high-risk patients younger than 45 years for prevention of anal SCC, including those with rectal squamous metaplasia.

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炎症性肠病中直肠鳞状皮化生的罕见发现。

直肠鳞状皮化生在炎症性肠病是罕见的。我们报告2例直肠鳞状皮化生，其中一例为克罗恩病患者，另一例为溃疡性结肠炎患者。鉴于恶性转化的风险，异常增生的监测是重要的，特别是在慢性炎症的区域。此外，人乳头状瘤病毒（HPV）参与了肛门鳞状细胞癌（SCC）的发病机制，但在美国没有针对炎症性肠病中肛门鳞状细胞癌的HPV预防指南。45岁以下的高危患者应考虑接种HPV疫苗，以预防肛门SCC，包括直肠鳞状皮化生患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.