The neural correlates of physical exercise-induced general cognitive gains: A systematic review and meta-analysis of functional magnetic resonance imaging studies

IF 7.5 1区医学 Q1 BEHAVIORAL SCIENCES

Neuroscience and Biobehavioral Reviews Pub Date : 2025-02-01 DOI:10.1016/j.neubiorev.2025.106008

Geng Li , Haishuo Xia , Gesi Teng , Antao Chen

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引用次数: 0

Abstract

The general-domain effect of physical exercise-induced cognitive gains in behavioral outcomes is well-documented, but a consensus on the neural correlates remains elusive. This meta-analysis aims to identify the neural correlates of physical exercise-induced general cognitive gains by examining task-related brain activation consistently modulated by physical exercise and its relationship to those gains. Our analysis of 52 studies with 1503 participants shows that physical exercise enhances cognitive task performance (Hedges' g = 0.271) and consistently increases task-related brain activation primarily in the bilateral precuneus. These increases in task-related brain activation correlate positively with cognitive task performance improvements improvements. Notably, physical exercise intensity, adherence, and social environment significantly modulate task-related brain activation changes induced by physical exercise. This meta-analysis offers an unprecedented comprehensive assessment of how physical exercise modulates task-related brain activation changes, providing neural evidence to support the general-domain effects on cognitive function induced by physical exercise.

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体育锻炼引起的一般认知增益的神经相关性：功能磁共振成像研究的系统回顾和荟萃分析。

体育锻炼在行为结果中诱导的认知增益的一般域效应已被充分证明，但关于神经相关性的共识仍未达成。本荟萃分析旨在通过研究体育锻炼持续调节的任务相关大脑激活及其与认知能力提高的关系，确定体育锻炼诱导的一般认知能力提高的神经相关因素。我们对 52 项研究、1,503 名参与者进行的分析表明，体育锻炼可提高任务绩效（赫奇斯 g = 0.271），并持续增加与任务相关的大脑激活，主要是在双侧楔前肌。这些任务相关大脑激活的增加与任务表现的提高呈正相关。值得注意的是，体育锻炼的强度、坚持程度和社会环境会显著调节体育锻炼引起的任务相关脑激活变化。这项荟萃分析对体育锻炼如何调节与任务相关的大脑激活变化进行了前所未有的全面评估，为体育锻炼对认知功能的一般领域影响提供了神经证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuroscience and Biobehavioral Reviews 医学-行为科学

CiteScore

14.20

自引率

3.70%

发文量

466

审稿时长

6 months

期刊介绍： The official journal of the International Behavioral Neuroscience Society publishes original and significant review articles that explore the intersection between neuroscience and the study of psychological processes and behavior. The journal also welcomes articles that primarily focus on psychological processes and behavior, as long as they have relevance to one or more areas of neuroscience.