Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-01-01 DOI:10.1016/j.tjog.2024.03.029

Kuang-Han Liu , Chia-Chin Tsai , Krystal Baysan Lin , Pei-Shen Huang

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引用次数: 0

Abstract

Objective

Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997.

Case report

A 61-year-old menopausal woman presented with abnormal vaginal bleeding. Despite no prior Papanicolaou smears and normal Pap results this time, transvaginal sonography revealed 7 mm endometrial thickening and elevated cancer antigen 125 (CA-125). Dilatation and curettage revealed atypical glands with squamous metaplasia. On May 3, 2017, she underwent robot-assisted staging surgery (stage IB) and pelvic radiotherapy. No disease recurrence observed till now.

Conclusion

Early diagnosis of PESCC is crucial for management. Although guidelines are lacking due to the rarity of PESCC, increased reporting and research are expected to shed light on this condition and facilitate the establishment of treatment protocols.

查看原文本刊更多论文

原发性子宫内膜鳞状细胞癌（PESCC）：文献回顾及病例报告。

目的：原发性子宫内膜鳞状细胞癌（PESCC）是一种极为罕见的子宫内膜癌，研究和认识有限。本报告介绍一例PESCC，并回顾了1997年以来的37例病例。病例报告：一61岁绝经妇女表现为阴道异常出血。尽管没有既往的巴氏涂片检查和正常的巴氏涂片检查结果，经阴道超声检查显示7mm子宫内膜增厚和癌抗原125 （CA-125）升高。扩张和刮除显示非典型腺体鳞状化生。2017年5月3日，她接受了机器人辅助分期手术（IB期）和盆腔放疗。至今未见疾病复发。结论：PESCC的早期诊断对治疗至关重要。尽管由于PESCC的罕见性，缺乏指导方针，但预计将增加报告和研究，以阐明这种情况，并促进建立治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.