Essential resources and best practices for laboratory mouse research

IF 3.7 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecules and Cells Pub Date : 2025-02-01 DOI:10.1016/j.mocell.2025.100178

Rosa Haque , Aysenur Deniz Song , Jongsun Lee , Seung-Jae V. Lee , Jae Myoung Suh

引用次数: 0

Abstract

The laboratory mouse (Mus musculus) is the most widely used mammalian model organism in biomedical and life science research. This concise guide aims to provide essential information to assist researchers new to working with mice, covering topics such as mouse husbandry, maintenance, and available resources for obtaining mouse strains and associated data. Additionally, we discuss ethical considerations, emphasizing the 3Rs (replacement, reduction, and refinement) to ensure responsible and humane research practices.

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实验室小鼠研究的基本资源和最佳实践。

实验小鼠（Mus musculus）是生物医学和生命科学研究中应用最广泛的哺乳动物模式生物。这本简明的指南旨在提供必要的信息，以协助研究人员与小鼠的新工作，涵盖主题，如小鼠饲养，维护，以及获取小鼠品系和相关数据的可用资源。此外，我们还讨论了伦理方面的考虑，强调3r（替代、减少和改进），以确保负责任和人道的研究实践。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecules and Cells 生物-生化与分子生物学

CiteScore

6.60

自引率

10.50%

发文量

审稿时长

2.3 months

期刊介绍： Molecules and Cells is an international on-line open-access journal devoted to the advancement and dissemination of fundamental knowledge in molecular and cellular biology. It was launched in 1990 and ISO abbreviation is "Mol. Cells". Reports on a broad range of topics of general interest to molecular and cell biologists are published. It is published on the last day of each month by the Korean Society for Molecular and Cellular Biology.