False-Positive Uptake of 123 I-MIBG in the Basal Ganglion in a Pediatric Neuroblastoma Patient.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI:10.1097/RLU.0000000000005661

Yanfeng Xu, Siqi Li, Xia Lu, Wei Wang, Jigang Yang

引用次数: 0

Abstract

Abstract: A 7-year-old boy with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT to evaluate the therapy response. The scan revealed abnormal 123 I-MIBG uptake in the left basal ganglion, indicating the possibility of brain metastasis. Subsequent contrast-enhanced brain MRI, however, did not show any abnormal signal intensity in the left basal ganglion. Follow-up 123 I-MIBG SPECT/CT scans at 3-month and 9-month also did not show abnormal MIBG uptake in the same area. The case highlights the possibility of false-positive uptake of 123 I-MIBG in the basal ganglion.

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小儿神经母细胞瘤患者基底神经节中123I-MIBG的假阳性摄取

摘要：一名患有高危神经母细胞瘤的7岁男孩接受了123I-MIBG SPECT/CT检查以评估治疗效果。扫描显示左侧基底神经节123I-MIBG摄取异常，提示脑转移的可能性。然而，随后的对比增强脑MRI未显示左侧基底神经节有任何异常信号强度。随访3个月和9个月的123I-MIBG SPECT/CT扫描也未显示同一区域的MIBG摄取异常。该病例强调了基底神经节中123I-MIBG假阳性摄取的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.