Particle manipulation under X-force fields.

IF 6.1 2区工程技术 Q1 BIOCHEMICAL RESEARCH METHODS

Lab on a Chip Pub Date : 2025-01-08 DOI:10.1039/d4lc00794h

Chundong Xue, Yifan Yin, Xiaoyu Xu, Kai Tian, Jinghong Su, Guoqing Hu

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引用次数: 0

Abstract

Particle manipulation is a central technique that enhances numerous scientific and medical applications by exploiting micro- and nanoscale control within fluidic environments. In this review, we systematically explore the multifaceted domain of particle manipulation under the influence of various X-force fields, integral to lab-on-a-chip technologies. We dissect the fundamental mechanisms of hydrodynamic, gravitational, optical, magnetic, electrical, and acoustic forces and detail their individual and synergistic applications. In particular, our discourse extends to advanced multi-modal manipulation strategies that harness the combined power of these forces, revealing their enhanced efficiency and precision in complex assays and diagnostic frameworks. The integration of cutting-edge technologies such as artificial intelligence and autonomous systems further enhances the capabilities of these microfluidic platforms, leading to transformative innovations in personalized medicine and point-of-care diagnostics. This review not only highlights current technological advances, but also forecasts the trajectory of future developments, emphasizing the escalating precision and scalability essential for advancing lab-on-a-chip applications.

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x力场下的粒子操纵。

粒子操纵是一项核心技术，通过在流体环境中开发微纳米级控制，增强了许多科学和医学应用。在这篇综述中，我们系统地探讨了在各种x力场影响下粒子操纵的多方面领域，这是芯片实验室技术的一部分。我们剖析了水动力、引力、光、磁、电和声学力的基本机制，并详细介绍了它们各自的和协同的应用。特别是，我们的论述扩展到先进的多模态操作策略，利用这些力量的综合力量，揭示其在复杂的分析和诊断框架中提高的效率和精度。人工智能和自主系统等尖端技术的集成进一步增强了这些微流控平台的能力，从而导致个性化医疗和即时诊断的变革性创新。这篇综述不仅强调了当前的技术进步，而且预测了未来发展的轨迹，强调了推进芯片实验室应用所必需的不断升级的精度和可扩展性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lab on a Chip 工程技术-化学综合

CiteScore

11.10

自引率

8.20%

发文量

434

审稿时长

2.6 months

期刊介绍： Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.