Runs of Homozygosity and Inferences in Wild Populations

IF 4.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Ecology Pub Date : 2025-01-06 DOI:10.1111/mec.17641

Aaron B. A. Shafer, Marty Kardos

引用次数: 0

Abstract

Long homozygous chromosome segments are known as runs of homozygosity (ROH); these reflect patterns of identity by descent and can be used to measure individual inbreeding, map recessive traits, and reconstruct demographic histories. Here, we review some key considerations with ROH detection and the inferences pertaining to inbreeding and demographic analyses in wild populations.

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野生种群纯合子序列及推断。

长纯合子染色体片段被称为纯合子序列（ROH）；这些反映了血统的身份模式，可以用来衡量个体近亲繁殖，绘制隐性性状图，重建人口历史。在这里，我们回顾了在野生种群中进行ROH检测的一些关键考虑因素以及与近亲繁殖和人口统计学分析有关的推论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Ecology 生物-进化生物学

CiteScore

8.40

自引率

10.20%

发文量

472

审稿时长

1 months

期刊介绍： Molecular Ecology publishes papers that utilize molecular genetic techniques to address consequential questions in ecology, evolution, behaviour and conservation. Studies may employ neutral markers for inference about ecological and evolutionary processes or examine ecologically important genes and their products directly. We discourage papers that are primarily descriptive and are relevant only to the taxon being studied. Papers reporting on molecular marker development, molecular diagnostics, barcoding, or DNA taxonomy, or technical methods should be re-directed to our sister journal, Molecular Ecology Resources. Likewise, papers with a strongly applied focus should be submitted to Evolutionary Applications. Research areas of interest to Molecular Ecology include: * population structure and phylogeography * reproductive strategies * relatedness and kin selection * sex allocation * population genetic theory * analytical methods development * conservation genetics * speciation genetics * microbial biodiversity * evolutionary dynamics of QTLs * ecological interactions * molecular adaptation and environmental genomics * impact of genetically modified organisms