Influence of Tacticity on the Self-Assembly of Poly(ethylene glycol)-b-poly(lactic acid) Block Copolymers

IF 5.1 Q1 POLYMER SCIENCE

ACS Macro Letters Pub Date : 2025-01-06 DOI:10.1021/acsmacrolett.4c00758

Sjoerd J. Rijpkema, B. Jelle Toebes, Jules van Vlaenderen, Liban van Haren, Daniela A. Wilson

引用次数: 0

Abstract

Lactide, possessing two stereocenters and thus three distinct configurations (DD, DL, and LL), serves as a captivating building block for polymers and self-assembly. Notably, polylactide (PLA) exhibits stereocomplexation, displaying heightened interactions between different configurations compared with interactions within the same configuration. This characteristic renders PLA an intriguing subject for investigating self-assembly behavior. In this study, 22 PEG-b-PLA polymers were synthesized and self-assembled, with analysis conducted through NMR and cryo-TEM techniques. A range of morphologies, including vesicles, diamond-shaped lamellae, and branched networks, were achieved by manipulating the tacticities. Enhanced comprehension of self-assembly interactions holds promise for advancing molecular recognition, self-replication, and asymmetric catalysis.

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来源期刊

ACS Macro Letters 化学-

CiteScore

10.40

自引率

3.40%

发文量

209

审稿时长

1 months

期刊介绍： ACS Macro Letters publishes research in all areas of contemporary soft matter science in which macromolecules play a key role, including nanotechnology, self-assembly, supramolecular chemistry, biomaterials, energy generation and storage, and renewable/sustainable materials. Submissions to ACS Macro Letters should justify clearly the rapid disclosure of the key elements of the study. The scope of the journal includes high-impact research of broad interest in all areas of polymer science and engineering, including cross-disciplinary research that interfaces with polymer science. With the launch of ACS Macro Letters, all Communications that were formerly published in Macromolecules and Biomacromolecules will be published as Letters in ACS Macro Letters.