Effects of Light and Laser Therapies on the Microecosystem of Sebaceous Glands in Acne Treatment.

IF 2.5 4区医学 Q2 DERMATOLOGY

Photodermatology, photoimmunology & photomedicine Pub Date : 2025-01-01 DOI:10.1111/phpp.70005

Jiaoxiong Xu, Shengbo Huang, Zhengzheng Fu, Wen Zheng, Wanting Luo, Niangqiao Zhuang, Liuhong Liu, Renliang He, Fang Yang

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引用次数: 0

Abstract

Background: Acne vulgaris (acne) is one of the most common skin diseases with complex pathogenesis. Numerous studies have shown that the microecosystem of sebaceous glands and Cutibacterium acnes play key roles in its pathogenesis. Antibiotics targeting C. acnes have been widely used in acne treatment, but the growing prevalence of antibiotic resistance has become alarming. Further research into the microecosystem of sebaceous glands and the role of specific C. acnes phylotypes in acne pathogenesis has led to a paradigm shift in acne treatment. Currently, non-antibiotic therapies such as light therapy and laser therapy are becoming increasingly popular, opening up new opportunities in acne management.

Methods: Studies on the microecosystem of sebaceous glands associated with acne and the effects of light and laser therapies on the microecosystem in acne treatment were retrieved from the PubMed database.

Results: Dysbiosis of the microecosystem of the pilosebaceous unit is closely related to the pathogenesis of acne. Light and laser therapies have an impact on the microecosystem of the pilosebaceous unit in acne treatment.

Conclusions: Light and laser therapies are the popular alternative options in acne treatment. The mechanisms of their effect on the microecosystem of sebaceous glands are not completely clear and require further research, especially for laser therapy.

查看原文本刊更多论文

光和激光治疗痤疮对皮脂腺微生态系统的影响。

背景：寻常痤疮是一种常见的皮肤病，发病机制复杂。大量研究表明，皮脂腺微生态系统和痤疮表皮杆菌在其发病中起关键作用。针对C. acnes的抗生素已广泛应用于痤疮的治疗，但抗生素耐药性的日益普遍已令人担忧。对皮脂腺微生态系统的进一步研究以及特定痤疮C.系统型在痤疮发病机制中的作用，导致痤疮治疗的范式转变。目前，非抗生素治疗如光疗和激光治疗越来越受欢迎，为痤疮治疗开辟了新的机会。方法：从PubMed数据库中检索与痤疮相关的皮脂腺微生态系统的研究，以及光和激光治疗痤疮对微生态系统的影响。结果：皮脂腺微生态系统的失调与痤疮的发病密切相关。在痤疮治疗中，光和激光治疗对毛囊皮脂腺单位的微生态系统有影响。结论：光和激光治疗是治疗痤疮的常用方法。它们对皮脂腺微生态系统的影响机制尚不完全清楚，需要进一步研究，特别是激光治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodermatology, photoimmunology & photomedicine 医学-皮肤病学

CiteScore

4.40

自引率

7.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal is a forum for new information about the direct and distant effects of electromagnetic radiation (ultraviolet, visible and infrared) mediated through skin. The divisions of the editorial board reflect areas of specific interest: aging, carcinogenesis, immunology, instrumentation and optics, lasers, photodynamic therapy, photosensitivity, pigmentation and therapy. Photodermatology, Photoimmunology & Photomedicine includes original articles, reviews, communications and editorials. Original articles may include the investigation of experimental or pathological processes in humans or animals in vivo or the investigation of radiation effects in cells or tissues in vitro. Methodology need have no limitation; rather, it should be appropriate to the question addressed.