Non-carcinogenic health risks assessment of bioaerosols.

IF 1.6 Q2 MULTIDISCIPLINARY SCIENCES
MethodsX Pub Date : 2024-12-09 DOI:10.1016/j.mex.2024.103088
Azhar Siddique, Kashif Rasool
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引用次数: 0

Abstract

Bioaerosols, pose potential health risks, yet quantitative assessments of non-carcinogenic risks from bioaerosol inhalation are limited. This study introduces a novel approach for assessing non-carcinogenic health risks using bioaerosol exposure data. The method employs the Average Daily Dose and Hazard Quotient (HQ) metrics, adapted from US Environmental Protection Agency guidelines, with the Reference Dose (RfD) based on thresholds from the National Institute of Occupational Safety and Health and the American Conference of Governmental Industrial Hygienists. This study utilizes a time-weighted approach, considering age-specific inhalation rates and body weights, to enhance the precision of lifetime exposure assessments. This methodology was applied to data collected over one year across multiple locations in Qatar, assessing seasonal and site-specific variations in risk. Results indicate generally low health risks, with HQ values below 1 for most sites and seasons. However, the study identified elevated HQ values at highly active sites during the dry summer, suggesting potential health concerns that need urgent attention. The proposed framework offers a replicable approach for evaluating bioaerosol-related health risks across diverse environments.
  • Novel adaptation of HQ-based risk assessment for bioaerosols in Qatar, incorporating a time-weighted approach.
  • Evaluation of seasonal and site-specific exposure dynamics.
  • Designed for replicability in different environmental conditions.

Abstract Image

生物气溶胶的非致癌健康风险评估。
生物气溶胶构成潜在的健康风险,但吸入生物气溶胶的非致癌风险的定量评估有限。本研究介绍了一种利用生物气溶胶暴露数据评估非致癌健康风险的新方法。该方法采用了根据美国环境保护署指南改编的平均日剂量和危害商(HQ)指标,参考剂量(RfD)基于美国国家职业安全与健康研究所和美国政府工业卫生学家会议的阈值。本研究采用时间加权方法,考虑特定年龄的吸入率和体重,以提高终身暴露评估的准确性。该方法应用于卡塔尔多个地点一年来收集的数据,评估了季节性和特定地点的风险变化。结果表明,健康风险总体较低,大部分地点和季节的HQ值低于1。然而,该研究发现,在干燥的夏季,在高度活跃的地点,HQ值升高,这表明需要紧急关注潜在的健康问题。拟议的框架为评估不同环境中与生物气溶胶相关的健康风险提供了一种可复制的方法。•卡塔尔基于hq的生物气溶胶风险评估的新适应,结合时间加权方法。•季节性和特定地点暴露动态的评估。•可在不同环境条件下复制。
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来源期刊
MethodsX
MethodsX Health Professions-Medical Laboratory Technology
CiteScore
3.60
自引率
5.30%
发文量
314
审稿时长
7 weeks
期刊介绍:
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