Antioxidant activity and protective effect of hydroxy derivatives of chalcones for sterlet (Acipenser ruthenus, Linnaeus, 1758) sperm

IF 2.3 3区生物学 Q2 BIOLOGY

Cryobiology Pub Date : 2025-01-01 DOI:10.1016/j.cryobiol.2024.105193

V.P. Osipova , M.N. Kolyada , M.A. Polovinkina , A.D. Kolumbet , E.N. Ponomareva , A.V. Velikorodov

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引用次数: 0

Abstract

The aim of this work is to study the effect of adding hydroxy derivatives of chalcones to the basic cryomedium on the ability of sterlet sperm to utilize superoxide and hydrogen peroxide, the intensity of lipid peroxidation of male fish germ cells, and their viability both before cryopreservation and after 3 days of freezing at liquid nitrogen temperature. The ability of phenolic derivatives of chalcones to increase the superoxide dismutase and catalase activities of sterlet sperm and to reduce the intensity of lipid peroxidation has been established. The antioxidant activity of the derivatives exceeds the effect of Trolox, which inhibits the functioning of the enzyme component of the antioxidant protection of fish sperm and promotes lipid peroxidation of fish sperm before cryopreservation. A beneficial effect of hydroxy derivatives of chalcones on the motility parameters of thawed sperm has been shown, indicating their ability to increase the cryoresistance of sperm in such a promising aquaculture species as sterlet.

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查尔酮羟基衍生物对小鲟（Acipenser ruthenus, Linnaeus, 1758）精子的抗氧化活性及保护作用

本研究旨在研究在基本低温培养基中添加查尔酮羟基衍生物对小体精子利用超氧化物和过氧化氢的能力、雄性鱼生殖细胞脂质过氧化强度以及冷冻前和液氮温度下冷冻3 d后生殖细胞活力的影响。查尔酮酚类衍生物具有提高小体精子超氧化物歧化酶和过氧化氢酶活性，降低脂质过氧化强度的作用。这些衍生物的抗氧化活性超过了Trolox的作用，它抑制了鱼精子抗氧化保护酶成分的功能，促进了鱼精子在冷冻前的脂质过氧化。查尔酮的羟基衍生物对解冻精子的运动参数有有益的影响，这表明它们能够提高小鱼等有前途的水产养殖物种精子的抗冻能力。

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来源期刊

Cryobiology 生物-生理学

CiteScore

5.40

自引率

7.40%

发文量

审稿时长

56 days

期刊介绍： Cryobiology: International Journal of Low Temperature Biology and Medicine publishes research articles on all aspects of low temperature biology and medicine. Research Areas include: • Cryoprotective additives and their pharmacological actions • Cryosurgery • Freeze-drying • Freezing • Frost hardiness in plants • Hibernation • Hypothermia • Medical applications of reduced temperature • Perfusion of organs • All pertinent methodologies Cryobiology is the official journal of the Society for Cryobiology.