Regenerative characteristics of the immortal jellyfish, Turritopsis dohrnii, and their potential implications for human aging

Q3 Medicine

Revista Espanola de Geriatria y Gerontologia Pub Date : 2024-12-23 DOI:10.1016/j.regg.2024.101607

Valentina Velasco-Muñoz , Mateo Uribe-Gaviria , Santiago Andrés Suárez-Gómez , Antonio Villamizar-Romero , Andrés Ricaurte-Fajardo , Isabel Cristina Vásquez-Vélez , Carlos A. Cano-Gutiérrez

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引用次数: 0

Abstract

The jellyfish Turritopsis dohrnii (T. Nutricala) is a cnidarian of the Oceaniidae family that lives in the Mediterranean Sea. It is known as the immortal jellyfish since, through a process of cell development called transdifferentiation, it manages to return to a polyp state. The role of regeneration processes and their impact on aging have been studied in recent years for their potential applications in the development of more efficient pharmacology to address disorders related to aging. Reviewing the terms related to transdifferentiation in jellyfish and understanding the underlying mechanisms can help comprehend diverse processes such as aging, regeneration, and the molecular bases of diseases like cancer. This paper's purpose is to provide a description of the regenerative characteristics of the jellyfish T. dohrnii, investigate how its regenerative processes allow it to rejuvenate, and determine if these tissue restoration processes are also found in humans.

查看原文本刊更多论文

不死水母杜氏灯塔水母的再生特性及其对人类衰老的潜在影响。

多氏灯塔水母（T. Nutricala）是生活在地中海的海洋生物科的一种刺胞动物。它之所以被称为不朽的水母，是因为它通过一种被称为转分化的细胞发育过程，成功地回到了水螅体状态。近年来，再生过程的作用及其对衰老的影响已被研究，以开发更有效的药理学来解决与衰老相关的疾病。回顾与水母转分化相关的术语，了解其潜在的机制，有助于理解衰老、再生等多种过程，以及癌症等疾病的分子基础。本文的目的是提供水母T. dohrnii再生特性的描述，研究其再生过程如何使其恢复活力，并确定这些组织恢复过程是否也存在于人类中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Espanola de Geriatria y Gerontologia Medicine-Medicine (miscellaneous)

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

85 days

期刊介绍： Una revista de gran prestigio por sus artículos originales de investigación y revisiones. Permite cubrir todas las áreas de la medicina pero siempre desde la atención al paciente anciano, y está presente en los más reconocidos índices internacionales.