Cryoneurolysis for management of post-mastectomy pain: a systematic review.

IF 1.4 Q4 CLINICAL NEUROLOGY

Pain management Pub Date : 2024-12-01 Epub Date: 2024-12-23 DOI:10.1080/17581869.2024.2443380

John DesRochers, Samantha Fry, Arwa Khadr, Neel Rana, Gilbert Siu

{"title":"Cryoneurolysis for management of post-mastectomy pain: a systematic review.","authors":"John DesRochers, Samantha Fry, Arwa Khadr, Neel Rana, Gilbert Siu","doi":"10.1080/17581869.2024.2443380","DOIUrl":null,"url":null,"abstract":"Aims: Post-mastectomy pain syndrome is a common postoperative complication that can impact patient quality of life and function. The aim of this systematic review is to evaluate the effectiveness of cryoneurolysis as an intervention for the management of post-mastectomy pain.Methods: A prospero-registered systematic review was performed following PRISMA 2020 guidelines. An initial screening consisted of 53 articles imported from the following databases: PubMed, Embase, Web of Science, Cochrane, and Scopus. Google Scholar and WorldCat were also searched to pull any further articles.Results: Three clinical trials, one case series, and one case report were included. Primary outcome measure of patient reported pain score (VAS or NRS) showed clinically significant reduction in pain in all five studies. Three of the studies also reported reduction in opioid use with cryoneurolysis intervention. A pooled effect size of Hedges g = -0.963, (95% CI [-1.55, -0.373]), with heterogeneity (I2 = 0.70).Conclusion: Cryoneurolysis intervention shows promising and clinically significant relief in post-mastectomy pain in patients and further studies are encouraged.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"665-671"},"PeriodicalIF":1.4000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pain management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17581869.2024.2443380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/23 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: Post-mastectomy pain syndrome is a common postoperative complication that can impact patient quality of life and function. The aim of this systematic review is to evaluate the effectiveness of cryoneurolysis as an intervention for the management of post-mastectomy pain.

Methods: A prospero-registered systematic review was performed following PRISMA 2020 guidelines. An initial screening consisted of 53 articles imported from the following databases: PubMed, Embase, Web of Science, Cochrane, and Scopus. Google Scholar and WorldCat were also searched to pull any further articles.

Results: Three clinical trials, one case series, and one case report were included. Primary outcome measure of patient reported pain score (VAS or NRS) showed clinically significant reduction in pain in all five studies. Three of the studies also reported reduction in opioid use with cryoneurolysis intervention. A pooled effect size of Hedges g = -0.963, (95% CI [-1.55, -0.373]), with heterogeneity (I² = 0.70).

Conclusion: Cryoneurolysis intervention shows promising and clinically significant relief in post-mastectomy pain in patients and further studies are encouraged.

查看原文本刊更多论文

冷冻神经松解术治疗乳房切除术后疼痛：系统综述。

目的：乳房切除术后疼痛综合征是一种常见的术后并发症，可影响患者的生活质量和功能。本系统综述的目的是评估冷冻神经松解术作为治疗乳房切除术后疼痛的干预措施的有效性。方法：按照PRISMA 2020指南进行普洛斯普洛斯注册的系统评价。初步筛选包括从以下数据库导入的53篇文章：PubMed， Embase, Web of Science， Cochrane和Scopus。谷歌Scholar和WorldCat也被搜索以获取更多的文章。结果：纳入3项临床试验，1个病例系列，1例病例报告。患者报告疼痛评分（VAS或NRS）的主要结局指标显示，在所有五项研究中，疼痛均有临床显著减轻。其中三项研究还报告了在冷冻神经溶解干预下阿片类药物使用的减少。Hedges的综合效应大小g = -0.963, (95% CI[-1.55, -0.373])，存在异质性（I2 = 0.70）。结论：冷冻神经溶解干预在缓解乳房切除术后患者疼痛方面具有临床意义，值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pain management CLINICAL NEUROLOGY-

CiteScore

2.90

自引率

5.90%

发文量